| Literature DB >> 35073839 |
Manna Li1, Le Deng1, Gaosi Xu2.
Abstract
Entities:
Year: 2022 PMID: 35073839 PMCID: PMC8787925 DOI: 10.1186/s10020-022-00437-0
Source DB: PubMed Journal: Mol Med ISSN: 1076-1551 Impact factor: 6.354
Fig. 2METTL14 promoted high glucose-induced glomerular endothelial cell injury. A Expression of METTL14 was examined by qRT-PCR after transfected with Vector or MELLT14 plasmid. **P < 0.01 vs. Vector. B Expression of METTL14 was examined by qRT-PCR after transfected with si-ctrl or MELLT14 siRNA. **P < 0.01 vs. si-Ctrl. C–E The levels of ROS, TNF-α and IL-6 were detected by ELISA. F Cell proliferation was assessed by CCK-8. G, H Cell apoptosis was analysed by TUNEL staining, Scale bar: 50 μm. *P < 0.05, **P < 0.01 vs. NG; #P < 0.05, ##P < 0.01 vs. HG + Vector; &P < 0.05, &&P < 0.01 vs. HG + si-Ctrl. Data are presented as the mean ± SD (n = 3)