Literature DB >> 35070147

Bone Marrow Aspirate Concentrate as a Reliable Adjunct in Tibiotalocalcanal Fusion: A Radiographic Modified RUST Score Analysis.

Bishoy N Saad1, David Zurita1, Deborah J Li2, Hannah Dailey3, Richard S Yoon1, Frank A Liporace1.   

Abstract

BACKGROUND: Tibiotalar and subtalar arthritis requiring tibiotalocalcaneal (TTC) fusion can be technically challenging and is dependent on reliable fusion for a good clinical outcome. Initial data regarding bone marrow aspirate concentrate (BMAC) has shown promise in use as an aide in both fracture and fusion healing. The purpose of this study is to determine the outcomes in TTC fusion when utilizing BMAC as an adjunct.
METHODS: Twenty consecutive patients who underwent TTC fusion with BMAC adjunct between March 2013 and November 2017 were retrospectively screened for inclusion. Patients were included regardless of comorbidities or risk factors for non-union, and only excluded if they did not have a minimum of 12 months of clinical and/or radiographic chart data. Follow-up was obtained at regular intervals of 6 weeks, 3 months, 6 months and 1 year. Modified RUST scores were applied to grade bony union in a blinded fashion by two orthopedic trauma fellowship-trained surgeons and agreement was assessed via intraclass correlation coefficient (ICC).
RESULTS: Twenty patients were screened and 12 met inclusion criteria for analysis. Majority were male (66.6%) at a mean age of 55.4 years and they were all treated via TTC fusion for a diagnosis of tibiotalar and subtalar arthritis. There were no postoperative complications and no reoperations in this cohort; no donor site morbidity was associated with BMAC. By the 3-month follow-up timepoint, all but one patient received a minimum modified RUST score of 10 indicating bony union (ICC 0.91); by the 6-month time point (ICC 0.94), all 12 patients were deemed united.
CONCLUSION: BMAC as an adjunct in the setting of TTC fusion is a safe treatment option that can promote reliable, consistent bony fusion with minimal complications. © Indian Orthopaedics Association 2021.

Entities:  

Keywords:  Ankle arthritis; BMAC; Hindfoot fusion; Subtalar arthritis; Subtalar fusion; TTC fusion; Tibiotalar arthritis

Year:  2021        PMID: 35070147      PMCID: PMC8748578          DOI: 10.1007/s43465-021-00425-2

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.033


  38 in total

1.  Revision tibiotalar arthrodesis.

Authors:  Mark E Easley; Harvey E Montijo; Joseph B Wilson; Robert D Fitch; James A Nunley
Journal:  J Bone Joint Surg Am       Date:  2008-06       Impact factor: 5.284

2.  The impact of diabetes on patient outcomes after ankle fracture.

Authors:  Shanti P Ganesh; Ricardo Pietrobon; William A C Cecílio; Deng Pan; Nina Lightdale; James A Nunley
Journal:  J Bone Joint Surg Am       Date:  2005-08       Impact factor: 5.284

3.  Development of the radiographic union score for tibial fractures for the assessment of tibial fracture healing after intramedullary fixation.

Authors:  Daniel B Whelan; Mohit Bhandari; David Stephen; Hans Kreder; Michael D McKee; Rad Zdero; Emil H Schemitsch
Journal:  J Trauma       Date:  2010-03

4.  Fracture of the body of the talus.

Authors:  O Sneppen; S B Christensen; O Krogsoe; J Lorentzen
Journal:  Acta Orthop Scand       Date:  1977

5.  Benefits of small volume and small syringe for bone marrow aspirations of mesenchymal stem cells.

Authors:  Philippe Hernigou; Yasuhiro Homma; Charles Henri Flouzat Lachaniette; Alexandre Poignard; Jerome Allain; Nathalie Chevallier; Helene Rouard
Journal:  Int Orthop       Date:  2013-07-24       Impact factor: 3.075

6.  Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease.

Authors:  Thomas D Brown; Richard C Johnston; Charles L Saltzman; J Lawrence Marsh; Joseph A Buckwalter
Journal:  J Orthop Trauma       Date:  2006 Nov-Dec       Impact factor: 2.512

7.  Determination of Radiographic Healing: An Assessment of Consistency Using RUST and Modified RUST in Metadiaphyseal Fractures.

Authors:  Jody Litrenta; Paul Tornetta; Samir Mehta; Clifford Jones; Robert V OʼToole; Mohit Bhandari; Stephen Kottmeier; Robert Ostrum; Kenneth Egol; William Ricci; Emil Schemitsch; Daniel Horwitz
Journal:  J Orthop Trauma       Date:  2015-11       Impact factor: 2.512

Review 8.  Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis. A systematic review of the literature.

Authors:  S L Haddad; J C Coetzee; R Estok; K Fahrbach; D Banel; L Nalysnyk
Journal:  J Bone Joint Surg Am       Date:  2007-09       Impact factor: 5.284

9.  Ankle arthrodesis. Problems and pitfalls.

Authors:  R J Hagen
Journal:  Clin Orthop Relat Res       Date:  1986-01       Impact factor: 4.176

10.  Influencing factors of functional result and bone union in tibiotalocalcaneal arthrodesis with intramedullary locking nail: a retrospective series of 30 cases.

Authors:  Jean-Baptiste Gross; Rémi Belleville; Arnaud Nespola; Jean-Manuel Poircuitte; Henry Coudane; Didier Mainard; Laurent Galois
Journal:  Eur J Orthop Surg Traumatol       Date:  2013-10-27
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