| Literature DB >> 35069037 |
Youssef Miyah1,2, Mohammed Benjelloun1, Sanae Lairini1, Anissa Lahrichi2.
Abstract
The end of the year 2019 was marked by the introduction of a third highly pathogenic coronavirus, after SARS-CoV (2003) and MERS-CoV (2012), in the human population which was officially declared a global pandemic by the World Health Organization (WHO) on March 11, 2020. Indeed, the pandemic of COVID-19 (Coronavirus Disease 19) has evolved at an unprecedented rate: after its emergence in Wuhan, the capital of the province of Hubei of the People's Republic of China, in December 2019, the total number of confirmed cases did not cease growing very quickly in the world. In this manuscript, we have provided an overview of the impact of COVID-19 on health, and we have proposed different nutrients suitable for infected patients to boost their immune systems. On the other hand, we have described the advantages and disadvantages of COVID-19 on the environment including the quality of water, air, waste management, and energy consumption, as well as the impact of this pandemic on human psychology, the educational system, and the global economy. In addition, we have tried to come up with some solutions to counter the negative repercussions of the pandemic.Entities:
Mesh:
Year: 2022 PMID: 35069037 PMCID: PMC8767375 DOI: 10.1155/2022/5578284
Source DB: PubMed Journal: ScientificWorldJournal ISSN: 1537-744X
Figure 1COVID-19 impacts on human health, environment, education system, and socioeconomy.
Nutritional support for COVID-19 patients.
| Type of nutrition or diet | Food description | Reference |
|---|---|---|
| Fish oil | Lipid emulsions: a large amount of energy in a small volume; high proportions of omega-3 acids are precursors to anti-inflammatory mediators such as eicosapentaenoic and docosahexaenoic acids | [ |
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| Vitamin C | Vitamin C could have a double effect: antioxidant: protects cells and tissues in the body from oxidative damage and dysfunction; immunoprotective: inhibits the secretion of lactate produced by activated immune cells and protects the innate immunity from angiotensin 2 | [ |
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| Vitamin D | Vitamin D improves lung function in patients with asthma, chronic obstructive pulmonary disease, or in smokers, especially if there is a vitamin D deficiency at the start. Calcidiol (calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D) has reliable intestinal absorption (close to 100%) and can quickly restore serum concentrations because it does not require hepatic 25-hydroxylation. When calcitriol (a hormonal metabolite of vitamin D) enters the nuclear receptor, a deoxyribonucleic acid-binding protein interacts with regulatory sequences near target genes and recruits active chromatin complexes that genetically and epigenetically alter production transcriptionally. Calcitriol regulates serum calcium concentration and, therefore, feeds back with parathyroid hormone. Vitamin D provides a physical barrier, natural cellular immunity through the induction of antimicrobial peptides, and a modulator of adaptive immunity against colds. Vitamin D reduces the production or expression of proinflammatory cytokines and increases the expression of anti-inflammatory cytokines by macrophages | [ |
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| Zinc | Improves immune function, improves resistance to infections, and increases the cytotoxic activity of natural killer cells, which can attack cells that have abnormal or unusual proteins in the plasma membrane. It is an anti-inflammatory agent, maintaining immune tolerance because it induces the development of Treg cells and attenuates the development of proinflammatory helper T cells 17 and helper T cells 9, in addition to being involved in the production of antibodies, in particular immunoglobulins | [ |
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| Vitamin A | Antiinfective vitamin | [ |
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| Required water | Maintaining adequate hydration remotes heart or renal failure and recent clinical history as diarrhea, vomiting, and electrolyte imbalances | |
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| Probiotics | Probiotics may be useful before intestinal dysbiosis with the decrease in bifidobacteria and lactobacilli. Micronutrient support of the intestine as well as the administration of a symbiotic (probiotics and prebiotics) restore balance and prevent the risk of secondary infection. In chronic inflammatory diseases, taking a high-concentration probiotic reduces the plasma levels of proinflammatory cytokines at the expense of those regulating inflammation, with changes in the fecal microbiota | [ |
Figure 2Impact of COVID-19 on the environment.