Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The significance of the SDF-1/CXCR4 signaling pathway in the normal development.

Literature DB >> 35067815

The significance of the SDF-1/CXCR4 signaling pathway in the normal development.

Farzad Sadri¹, Zohreh Rezaei^2,3, Mohammad Fereidouni^4,5.

Abstract

Chemokines are chemoattractants that can regulate cell movement and adhesion. SDF-1 [stromal cell-derived factor-1 (SDF-1)] is a homeostatic CXC chemokine. SDF-1 and its receptors [CXC chemokine receptor 4 (CXCR4)] form a signaling pathway that plays critical roles in different pathological and physiological mechanisms, including embryogenesis, wound healing, angiogenesis, tumor growth, and proliferation. Therefore, the current review aimed to summarize the related studies that addressed the molecular signature of the SDF-1/CXCR4 pathway and to explain how this axis is involved in normal events.

Entities: Chemical

Keywords: CXCR4; Chemokines; Migration; SDF-1; Stem cells

Mesh：

Substances：

Year: 2022 PMID： 35067815 DOI： 10.1007/s11033-021-07069-3

Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316

95 in total

Review 1. Chemokines: a new classification system and their role in immunity.

Authors: A Zlotnik; O Yoshie
Journal: Immunity Date: 2000-02 Impact factor: 31.745

Review 2. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

Authors: M Z Ratajczak; E Zuba-Surma; M Kucia; R Reca; W Wojakowski; J Ratajczak
Journal: Leukemia Date: 2006-08-10 Impact factor: 11.528

Review 3. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

Authors: S F Altschul; T L Madden; A A Schäffer; J Zhang; Z Zhang; W Miller; D J Lipman
Journal: Nucleic Acids Res Date: 1997-09-01 Impact factor: 16.971

Review 4. CXCL12 (SDF-1)/CXCR4 pathway in cancer.

Authors: Beverly A Teicher; Simon P Fricker
Journal: Clin Cancer Res Date: 2010-05-18 Impact factor: 12.531

Review 5. New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

Authors: Andrew B Kleist; Anthony E Getschman; Joshua J Ziarek; Amanda M Nevins; Pierre-Arnaud Gauthier; Andy Chevigné; Martyna Szpakowska; Brian F Volkman
Journal: Biochem Pharmacol Date: 2016-04-19 Impact factor: 5.858

6. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization.

Authors: Jun-ichi Yamaguchi; Kengo Fukushima Kusano; Osamu Masuo; Atsuhiko Kawamoto; Marcy Silver; Satoshi Murasawa; Marta Bosch-Marce; Haruchika Masuda; Douglas W Losordo; Jeffrey M Isner; Takayuki Asahara
Journal: Circulation Date: 2003-03-11 Impact factor: 29.690

7. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

Authors: M P Crump; J H Gong; P Loetscher; K Rajarathnam; A Amara; F Arenzana-Seisdedos; J L Virelizier; M Baggiolini; B D Sykes; I Clark-Lewis
Journal: EMBO J Date: 1997-12-01 Impact factor: 11.598

The significance of the SDF-1/CXCR4 signaling pathway in the normal development.

Review 1. Chemokines: a new classification system and their role in immunity.

Review 2. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

Review 3. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

Review 4. CXCL12 (SDF-1)/CXCR4 pathway in cancer.

Review 5. New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

6. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization.

7. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

Review 8. Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.

9. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene.

Review 10. Chemokine receptors: multifaceted therapeutic targets.

1. Antiviral Activity of a Cyclic Pro-Pro-β³-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5.

The significance of the SDF-1/CXCR4 signaling pathway in the normal development.

Review 1. Chemokines: a new classification system and their role in immunity.

Review 2. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

Review 3. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

Review 4. CXCL12 (SDF-1)/CXCR4 pathway in cancer.

Review 5. New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

6. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization.

7. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

Review 8. Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.

9. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene.

Review 10. Chemokine receptors: multifaceted therapeutic targets.

1. Antiviral Activity of a Cyclic Pro-Pro-β3-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5.

1. Antiviral Activity of a Cyclic Pro-Pro-β³-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5.