Literature DB >> 35067099

Underutilization of Endovascular Therapy in Black Patients With Ischemic Stroke: An Analysis of State and Nationwide Cohorts.

Youngran Kim1, Anjail Sharrief1, Min Ji Kwak2, Swapnil Khose1, Rania Abdelkhaleq1, Sergio Salazar-Marioni1, Guo-Qiang Zhang1, Sunil A Sheth1.   

Abstract

BACKGROUND AND
PURPOSE: Endovascular therapy (EVT) is a very effective treatment but relies on specialized capabilities that are not available in every hospital where acute ischemic stroke is treated. Here, we assess whether access to and utilization of this therapy has extended uniformly across racial and ethnic groups.
METHODS: We conducted a retrospective, population-based study using the 2019 Texas Inpatient Public Use Data File. Acute ischemic stroke cases and EVT use were identified using the International Classification of Diseases, Tenth Revision (ICD-10) diagnosis and procedure codes. We examined EVT utilization by race/ethnicity and performed patient- and hospital-level analyses. To validate state-specific findings, we conducted patient-level analyses using the 2017 National Inpatient Sample for national estimates. To assess independent associations between race/ethnicity and EVT, multivariable modified Poisson regressions were fitted and adjusted relative risks were estimated accounting for patient risk factors and socioeconomic characteristics.
RESULTS: Among 40 814 acute ischemic stroke cases in Texas in 2019, 54% were White, 17% Black, and 21% Hispanic. Black patients had similar admissions to EVT-performing hospitals and greater admissions to comprehensive stroke centers (CSCs) compared with White patients (EVT 62% versus 62%, P=0.21; CSCs 45% versus 39%, P<0.001) but had lower EVT rates (4.1% versus 5.3%; adjusted relative risk, 0.76 [0.66-0.88]; P<0.001). There were no differences in EVT rates between Hispanic and White patients. Lower rates of EVT among Black patients were consistent in the subgroup of patients who arrived in early time windows and received intravenous recombinant tissue-type plasminogen activator (adjusted relative risk, 0.77 [0.61-0.98]; P=0.032) and the subgroup of those admitted to EVT-performing hospitals in both non-CSC (3.0% versus 5.5, P<0.001) and CSC hospitals (7.9% versus 10.4%, P<0.001) while there were no differences between Whites and Hispanic patients. Nationwide sample data confirmed this finding of lower utilization of EVT among Black patients (adjusted relative risk, 0.87 [0.77-0.98]; P=0.024).
CONCLUSIONS: We found no evidence of disparity in presentation to EVT-performing hospitals or CSCs; however, lower rates of EVT were observed in Black patients.

Entities:  

Keywords:  endovascular procedures; ethnicity; healthcare disparities; ischemic stroke; socioeconomic factors; thrombectomy; tissue-type plasminogen activator

Mesh:

Substances:

Year:  2022        PMID: 35067099      PMCID: PMC8979555          DOI: 10.1161/STROKEAHA.121.035714

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  32 in total

1.  Racial/ethnic disparities in emergency department waiting time for stroke patients in the United States.

Authors:  Sudeep J Karve; Rajesh Balkrishnan; Yousef M Mohammad; Deborah A Levine
Journal:  J Stroke Cerebrovasc Dis       Date:  2010-06-09       Impact factor: 2.136

2.  A modified poisson regression approach to prospective studies with binary data.

Authors:  Guangyong Zou
Journal:  Am J Epidemiol       Date:  2004-04-01       Impact factor: 4.897

3.  Racial and Ethnic Disparities in the Utilization of Thrombectomy for Acute Stroke.

Authors:  Lorenzo Rinaldo; Alejandro A Rabinstein; Harry Cloft; John M Knudsen; Leonardo Rangel Castilla; Waleed Brinjikji
Journal:  Stroke       Date:  2019-08-01       Impact factor: 7.914

4.  Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.

Authors:  Raul G Nogueira; Ashutosh P Jadhav; Diogo C Haussen; Alain Bonafe; Ronald F Budzik; Parita Bhuva; Dileep R Yavagal; Marc Ribo; Christophe Cognard; Ricardo A Hanel; Cathy A Sila; Ameer E Hassan; Monica Millan; Elad I Levy; Peter Mitchell; Michael Chen; Joey D English; Qaisar A Shah; Frank L Silver; Vitor M Pereira; Brijesh P Mehta; Blaise W Baxter; Michael G Abraham; Pedro Cardona; Erol Veznedaroglu; Frank R Hellinger; Lei Feng; Jawad F Kirmani; Demetrius K Lopes; Brian T Jankowitz; Michael R Frankel; Vincent Costalat; Nirav A Vora; Albert J Yoo; Amer M Malik; Anthony J Furlan; Marta Rubiera; Amin Aghaebrahim; Jean-Marc Olivot; Wondwossen G Tekle; Ryan Shields; Todd Graves; Roger J Lewis; Wade S Smith; David S Liebeskind; Jeffrey L Saver; Tudor G Jovin
Journal:  N Engl J Med       Date:  2017-11-11       Impact factor: 91.245

5.  Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.

Authors:  Jeffrey L Saver; Mayank Goyal; Alain Bonafe; Hans-Christoph Diener; Elad I Levy; Vitor M Pereira; Gregory W Albers; Christophe Cognard; David J Cohen; Werner Hacke; Olav Jansen; Tudor G Jovin; Heinrich P Mattle; Raul G Nogueira; Adnan H Siddiqui; Dileep R Yavagal; Blaise W Baxter; Thomas G Devlin; Demetrius K Lopes; Vivek K Reddy; Richard du Mesnil de Rochemont; Oliver C Singer; Reza Jahan
Journal:  N Engl J Med       Date:  2015-04-17       Impact factor: 91.245

6.  Utilization and Availability of Advanced Imaging in Patients With Acute Ischemic Stroke.

Authors:  Youngran Kim; Songmi Lee; Rania Abdelkhaleq; Victor Lopez-Rivera; Babak Navi; Hooman Kamel; Sean I Savitz; Alexandra L Czap; James C Grotta; Louise D McCullough; Trudy Millard Krause; Luca Giancardo; Farhaan S Vahidy; Sunil A Sheth
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2021-03-24

7.  Endovascular therapy for ischemic stroke with perfusion-imaging selection.

Authors:  Bruce C V Campbell; Peter J Mitchell; Timothy J Kleinig; Helen M Dewey; Leonid Churilov; Nawaf Yassi; Bernard Yan; Richard J Dowling; Mark W Parsons; Thomas J Oxley; Teddy Y Wu; Mark Brooks; Marion A Simpson; Ferdinand Miteff; Christopher R Levi; Martin Krause; Timothy J Harrington; Kenneth C Faulder; Brendan S Steinfort; Miriam Priglinger; Timothy Ang; Rebecca Scroop; P Alan Barber; Ben McGuinness; Tissa Wijeratne; Thanh G Phan; Winston Chong; Ronil V Chandra; Christopher F Bladin; Monica Badve; Henry Rice; Laetitia de Villiers; Henry Ma; Patricia M Desmond; Geoffrey A Donnan; Stephen M Davis
Journal:  N Engl J Med       Date:  2015-02-11       Impact factor: 91.245

8.  Patterns of emergency medical services use and its association with timely stroke treatment: findings from Get With the Guidelines-Stroke.

Authors:  Olaniyi James Ekundayo; Jeffrey L Saver; Gregg C Fonarow; Lee H Schwamm; Ying Xian; Xin Zhao; Adrian F Hernandez; Eric D Peterson; Eric M Cheng
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2013-04-29

9.  Validity of Race and Ethnicity Codes in Medicare Administrative Data Compared With Gold-standard Self-reported Race Collected During Routine Home Health Care Visits.

Authors:  Olga F Jarrín; Abner N Nyandege; Irina B Grafova; XinQi Dong; Haiqun Lin
Journal:  Med Care       Date:  2020-01       Impact factor: 3.178

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