Literature DB >> 35064389

Ring-ing in the Future: Participant and Male Partner Perspectives Regarding Future Use of the Dapivirine Vaginal Ring for HIV Prevention.

Krishnaveni Reddy1, Florence Mathebula2, Ariana Katz3, Ellen Luecke3, Siyanda Tenza2, Thesla Palanee-Phillips2, Morgan Garcia4, Leila E Mansoor5, Sarita Naidoo6,7, Neetha Morar6, Miria Chitukuta8, Mercy Tsidya9, Elizabeth T Montgomery3.   

Abstract

Women account for a disproportionate percentage of new HIV infections in sub-Saharan Africa indicating a need for female-initiated HIV prevention options congruent with their lifestyles. The dapivirine vaginal ring for HIV prevention is one such option. We explored the interest of women, who used this ring during the Microbicide Trials Network's ASPIRE and HOPE studies, in using the ring post-licensure and what they perceived as important considerations for future use. We also explored perspectives of HOPE participants' male partners on their involvement in their partners' future ring use. Women appeared keen to use the ring in the future and expressed desires for easy access, support for both ongoing and new users and intense community engagement. In parallel, male partners indicated high levels of interest in supporting their partners' ring use and being involved in ring use decision making. These data offer important insights for ring rollout planning and engagement activities.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Dapivirine vaginal ring; Future use; HIV prevention

Mesh:

Substances:

Year:  2022        PMID: 35064389      PMCID: PMC9050873          DOI: 10.1007/s10461-021-03542-z

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  23 in total

1.  Tenofovir 1% vaginal gel for prevention of HIV-1 infection in women in South Africa (FACTS-001): a phase 3, randomised, double-blind, placebo-controlled trial.

Authors:  Sinead Delany-Moretlwe; Carl Lombard; Deborah Baron; Linda-Gail Bekker; Busi Nkala; Khatija Ahmed; Modulakgotla Sebe; William Brumskine; Maposhane Nchabeleng; Thesla Palanee-Philips; Julius Ntshangase; Sidney Sibiya; Emilee Smith; Ravindre Panchia; Landon Myer; Jill L Schwartz; Mark Marzinke; Lynn Morris; Elizabeth R Brown; Gustavo F Doncel; Glenda Gray; Helen Rees
Journal:  Lancet Infect Dis       Date:  2018-10-24       Impact factor: 25.071

2.  Reasons for nonadherence to the dapivirine vaginal ring: narrative explanations of objective drug-level results.

Authors:  Elizabeth T Montgomery; Jonathan Stadler; Sarita Naidoo; Ariana W K Katz; Nicole Laborde; Morgan Garcia; Krishnaveni Reddy; Leila E Mansoor; Juliane Etima; Chifundo Zimba; Miria Chitukuta; Lydia Soto-Torres
Journal:  AIDS       Date:  2018-07-17       Impact factor: 4.177

3.  Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.

Authors:  Jared M Baeten; Thesla Palanee-Phillips; Elizabeth R Brown; Katie Schwartz; Lydia E Soto-Torres; Vaneshree Govender; Nyaradzo M Mgodi; Flavia Matovu Kiweewa; Gonasagrie Nair; Felix Mhlanga; Samantha Siva; Linda-Gail Bekker; Nitesha Jeenarain; Zakir Gaffoor; Francis Martinson; Bonus Makanani; Arendevi Pather; Logashvari Naidoo; Marla Husnik; Barbra A Richardson; Urvi M Parikh; John W Mellors; Mark A Marzinke; Craig W Hendrix; Ariane van der Straten; Gita Ramjee; Zvavahera M Chirenje; Clemensia Nakabiito; Taha E Taha; Judith Jones; Ashley Mayo; Rachel Scheckter; Jennifer Berthiaume; Edward Livant; Cindy Jacobson; Patrick Ndase; Rhonda White; Karen Patterson; Donna Germuga; Beth Galaska; Katherine Bunge; Devika Singh; Daniel W Szydlo; Elizabeth T Montgomery; Barbara S Mensch; Kristine Torjesen; Cynthia I Grossman; Nahida Chakhtoura; Annalene Nel; Zeda Rosenberg; Ian McGowan; Sharon Hillier
Journal:  N Engl J Med       Date:  2016-02-22       Impact factor: 91.245

4.  Male Partner Influence on Women's HIV Prevention Trial Participation and Use of Pre-exposure Prophylaxis: the Importance of "Understanding".

Authors:  Elizabeth T Montgomery; Ariane van der Straten; Jonathan Stadler; Miriam Hartmann; Busisiwe Magazi; Florence Mathebula; Nicole Laborde; Lydia Soto-Torres
Journal:  AIDS Behav       Date:  2015-05

5.  Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women.

Authors:  Annalene Nel; Neliëtte van Niekerk; Saidi Kapiga; Linda-Gail Bekker; Cynthia Gama; Katherine Gill; Anatoli Kamali; Philip Kotze; Cheryl Louw; Zonke Mabude; Nokuthula Miti; Sylvia Kusemererwa; Hugo Tempelman; Hannelie Carstens; Brid Devlin; Michelle Isaacs; Mariëtte Malherbe; Winel Mans; Jeremy Nuttall; Marisa Russell; Smangaliso Ntshele; Marlie Smit; Leonard Solai; Patrick Spence; John Steytler; Kathleen Windle; Maarten Borremans; Sophie Resseler; Jens Van Roey; Wim Parys; Tony Vangeneugden; Ben Van Baelen; Zeda Rosenberg
Journal:  N Engl J Med       Date:  2016-12-01       Impact factor: 91.245

6.  Qualitative Perceptions of Dapivirine VR Adherence and Drug Level Feedback Following an Open-Label Extension Trial.

Authors:  Kalendri Naidoo; Leila E Mansoor; Ariana W K Katz; Morgan Garcia; Doreen Kemigisha; Neetha S Morar; Chifundo C Zimba; Miria Chitukuta; Krishnaveni Reddy; Lydia Soto-Torres; Sarita Naidoo; Elizabeth T Montgomery
Journal:  J Acquir Immune Defic Syndr       Date:  2021-04-01       Impact factor: 3.731

7.  Men's Sexual Experiences with the Dapivirine Vaginal Ring in Malawi, South Africa, Uganda and Zimbabwe.

Authors:  Elizabeth T Montgomery; Ariana W K Katz; Zoe Duby; Leila E Mansoor; Neetha S Morar; Kalendri Naidoo; Mercy Tsidya; Miria Chitukuta; Victor Guma; Siyanda Tenza; Jonah Leslie; Morgan Garcia; Sarita Naidoo
Journal:  AIDS Behav       Date:  2021-01-02

8.  "You talk about problems until you feel free": South African adolescent girls' and young women's narratives on the value of HIV prevention peer support clubs.

Authors:  Deborah Baron; Fiona Scorgie; Lethabo Ramskin; Nomhle Khoza; Jennifer Schutzman; Anne Stangl; Sheila Harvey; Sinead Delany-Moretlwe
Journal:  BMC Public Health       Date:  2020-06-26       Impact factor: 3.295

9.  Impact and experience of participant engagement activities in supporting dapivirine ring use among participants enrolled in the phase III MTN-020/ASPIRE study.

Authors:  Morgan Garcia; Ellen Luecke; Ashley J Mayo; Rachel Scheckter; Patrick Ndase; Flavia Matovu Kiweewa; Doreen Kemigisha; Petina Musara; Leila E Mansoor; Nishanta Singh; Kubashni Woeber; Neetha S Morar; Nitesha Jeenarain; Zakir Gaffoor; Daniel K Gondwe; Yvonne Makala; Llewellyn Fleurs; Krishnaveni Reddy; Thesla Palanee-Phillips; Jared M Baeten; Ariane van der Straten; Lydia Soto-Torres; Kristine Torjesen
Journal:  BMC Public Health       Date:  2021-11-08       Impact factor: 4.135

10.  HIV Infection and AIDS in Sub-Saharan Africa: Current Status, Challenges and Opportunities.

Authors:  Ayesha B M Kharsany; Quarraisha A Karim
Journal:  Open AIDS J       Date:  2016-04-08
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