Literature DB >> 35064059

Reproductive Factors Do Not Influence Survival with Ovarian Cancer.

Minh Tung Phung1, Aliya Alimujiang1, Andrew Berchuck2, Hoda Anton-Culver3, Joellen M Schildkraut4, Elisa V Bandera5, Jenny Chang-Claude6,7, Anne Chase8, Jennifer Anne Doherty9, Bronwyn Grout8, Marc T Goodman10,11, Gillian E Hanley12, Alice W Lee13, Cindy McKinnon Deurloo8, Usha Menon14, Francesmary Modugno15,16,17, Paul D P Pharoah18,19, Malcolm C Pike20,21, Jean Richardson8,20, Harvey A Risch22, Weiva Sieh23,24, Kathryn L Terry25,26, Penelope M Webb27, Nicolas Wentzensen28, Anna H Wu20, Celeste Leigh Pearce1.   

Abstract

BACKGROUND: Previous studies on the association between reproductive factors and ovarian cancer survival are equivocal, possibly due to small sample sizes.
METHODS: Using data on 11,175 people diagnosed with primary invasive epithelial ovarian, fallopian tube, or primary peritoneal cancer (ovarian cancer) from 16 studies in the Ovarian Cancer Association Consortium (OCAC), we examined the associations between survival and age at menarche, combined oral contraceptive use, parity, breastfeeding, age at last pregnancy, and menopausal status using Cox proportional hazard models. The models were adjusted for age at diagnosis, race/ethnicity, education level, and OCAC study and stratified on stage and histotype.
RESULTS: During the mean follow-up of 6.34 years (SD = 4.80), 6,418 patients passed away (57.4%). There was no evidence of associations between the reproductive factors and survival among patients with ovarian cancer overall or by histotype.
CONCLUSIONS: This study found no association between reproductive factors and survival after an ovarian cancer diagnosis. IMPACT: Reproductive factors are well-established risk factors for ovarian cancer, but they are not associated with survival after a diagnosis of ovarian cancer. ©2022 American Association for Cancer Research.

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Year:  2022        PMID: 35064059      PMCID: PMC9444326          DOI: 10.1158/1055-9965.EPI-21-1091

Source DB:  PubMed          Journal:  Cancer Epidemiol Biomarkers Prev        ISSN: 1055-9965            Impact factor:   4.090


  8 in total

1.  Oral Contraceptive Use and Reproductive Characteristics Affect Survival in Patients With Epithelial Ovarian Cancer: A Cohort Study.

Authors:  Nonna V Kolomeyevskaya; J Brian Szender; Gary Zirpoli; Albina Minlikeeva; Grace Friel; Rikki A Cannioto; Rachel M Brightwell; Kassondra S Grzankowski; Kirsten B Moysich
Journal:  Int J Gynecol Cancer       Date:  2015-11       Impact factor: 3.437

2.  Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies.

Authors:  Camilla Praestegaard; Allan Jensen; Signe M Jensen; Thor S S Nielsen; Penelope M Webb; Christina M Nagle; Anna DeFazio; Estrid Høgdall; Mary Anne Rossing; Jennifer A Doherty; Kristine G Wicklund; Marc T Goodman; Francesmary Modugno; Kirsten Moysich; Roberta B Ness; Robert Edwards; Keitaro Matsuo; Satoyo Hosono; Ellen L Goode; Stacey J Winham; Brooke L Fridley; Daniel W Cramer; Kathryn L Terry; Joellen M Schildkraut; Andrew Berchuck; Elisa V Bandera; Lisa E Paddock; Leon F Massuger; Nicolas Wentzensen; Paul Pharoah; Honglin Song; Alice Whittemore; Valerie McGuire; Weiva Sieh; Joseph Rothstein; Hoda Anton-Culver; Argyrios Ziogas; Usha Menon; Simon A Gayther; Susan J Ramus; Alexandra Gentry-Maharaj; Anna H Wu; Celeste L Pearce; Malcolm Pike; Alice W Lee; Rebecca Sutphen; Jenny Chang-Claude; Harvey A Risch; Susanne K Kjaer
Journal:  Int J Cancer       Date:  2017-01-24       Impact factor: 7.396

3.  Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival.

Authors:  Katharine K Brieger; Siri Peterson; Alice W Lee; Bhramar Mukherjee; Kelly M Bakulski; Aliya Alimujiang; Hoda Anton-Culver; Michael S Anglesio; Elisa V Bandera; Andrew Berchuck; David D L Bowtell; Georgia Chenevix-Trench; Kathleen R Cho; Daniel W Cramer; Anna DeFazio; Jennifer A Doherty; Renée T Fortner; Dale W Garsed; Simon A Gayther; Aleksandra Gentry-Maharaj; Ellen L Goode; Marc T Goodman; Holly R Harris; Estrid Høgdall; David G Huntsman; Hui Shen; Allan Jensen; Sharon E Johnatty; Susan J Jordan; Susanne K Kjaer; Jolanta Kupryjanczyk; Diether Lambrechts; Karen McLean; Usha Menon; Francesmary Modugno; Kirsten Moysich; Roberta Ness; Susan J Ramus; Jean Richardson; Harvey Risch; Mary Anne Rossing; Britton Trabert; Nicolas Wentzensen; Argyrios Ziogas; Kathryn L Terry; Anna H Wu; Gillian E Hanley; Paul Pharoah; Penelope M Webb; Malcolm C Pike; Celeste Leigh Pearce
Journal:  Gynecol Oncol       Date:  2020-07-06       Impact factor: 5.482

4.  Identification of prognostic factors in advanced epithelial ovarian carcinoma.

Authors:  D S Chi; J B Liao; L F Leon; E S Venkatraman; M L Hensley; D Bhaskaran; W J Hoskins
Journal:  Gynecol Oncol       Date:  2001-09       Impact factor: 5.482

5.  Influence of reproductive factors on mortality after epithelial ovarian cancer diagnosis.

Authors:  Cheryl L Robbins; Maura K Whiteman; Susan D Hillis; Kathryn M Curtis; Jill A McDonald; Phyllis A Wingo; Aniket Kulkarni; Polly A Marchbanks
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2009-07       Impact factor: 4.254

6.  Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium.

Authors:  C M Nagle; S C Dixon; A Jensen; S K Kjaer; F Modugno; A deFazio; S Fereday; J Hung; S E Johnatty; P A Fasching; M W Beckmann; D Lambrechts; I Vergote; E Van Nieuwenhuysen; S Lambrechts; H A Risch; M A Rossing; J A Doherty; K G Wicklund; J Chang-Claude; M T Goodman; R B Ness; K Moysich; F Heitz; A du Bois; P Harter; I Schwaab; K Matsuo; S Hosono; E L Goode; R A Vierkant; M C Larson; B L Fridley; C Høgdall; J M Schildkraut; R P Weber; D W Cramer; K L Terry; E V Bandera; L Paddock; L Rodriguez-Rodriguez; N Wentzensen; H P Yang; L A Brinton; J Lissowska; E Høgdall; L Lundvall; A Whittemore; V McGuire; W Sieh; J Rothstein; R Sutphen; H Anton-Culver; A Ziogas; C L Pearce; A H Wu; P M Webb
Journal:  Br J Cancer       Date:  2015-07-07       Impact factor: 7.640

7.  Reproductive and hormonal factors in relation to survival and platinum resistance among ovarian cancer cases.

Authors:  Amy L Shafrir; Ana Babic; Rulla M Tamimi; Bernard A Rosner; Shelley S Tworoger; Kathryn L Terry
Journal:  Br J Cancer       Date:  2016-10-04       Impact factor: 7.640

8.  Epidemiologic factors that predict long-term survival following a diagnosis of epithelial ovarian cancer.

Authors:  Shana J Kim; Barry Rosen; Isabel Fan; Anna Ivanova; John R McLaughlin; Harvey Risch; Steven A Narod; Joanne Kotsopoulos
Journal:  Br J Cancer       Date:  2017-02-16       Impact factor: 7.640

  8 in total

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