Literature DB >> 35064053

Prospective cohort study of topical versus general anaesthesia for flexible bronchoscopy.

Di Feng1, Ye Gu2, Li Liu3, Lei Shen4, Hong Shi5.   

Abstract

BACKGROUND: Topical anaesthesia (TA) and general anaesthesia (GA) are performed for flexible bronchoscopy (FB) worldwide. However, few studies have compared the two anaesthesia methods in terms of perioperative discomforts.
METHODS: 648 patients undergoing FB were recruited in Shanghai Pulmonary Hospital, a specialised medical centre in China, from January 2019 to December 2019. The patients underwent FB under TA or GA. The TA group received 1% lidocaine by nasal route, and the GA group received total intravenous anaesthesia. The level of perioperative discomfort and patient satisfaction were assessed. The investigators were blind to the group allocation.
RESULTS: Finally, 239 patients received TA and 182 patients received GA. The basic demographic properties were comparable between two groups. There were no significant differences in terms of sore throat, 61.5% in TA group vs 57.1% in GA group. However, there was a significant difference in terms of postoperative nausea and vomiting (34.3% in TA group vs 56.6% in GA group), and dizziness (37.7% in TA group vs 78% in GA group). There was a significant difference in terms of total complication scores (17.2±5.1 in TA group vs 7.7±4.3 in GA group) and satisfaction degree of patients (2.6±1.1 in TA group vs 4.3±0.8 in GA group).
CONCLUSIONS: Compared with TA, GA significantly reduced the total complication scores of perioperative discomforts and improved the satisfaction score of patients for FB. TRIAL REGISTRATION NUMBER: This clinical trial was registered with www.chictr.org.cn (ChiCTR1800019971). © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  adult anaesthesia; bronchoscopy

Year:  2022        PMID: 35064053     DOI: 10.1136/postgradmedj-2021-141359

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  1 in total

1.  The Efficacy and Safety of Remimazolam Tosilate Versus Dexmedetomidine in Outpatients Undergoing Flexible Bronchoscopy: A Prospective, Randomized, Blind, Non-Inferiority Trial.

Authors:  Xingfang Chen; Deqian Xin; Guangjun Xu; Jing Zhao; Qing Lv
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

  1 in total

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