Literature DB >> 35059003

Meet the IUPAB councilor - Angela M. Gronenborn.

Angela M Gronenborn1.   

Abstract

As an incoming IUPAB Councilor, I have been asked to write a short commentary describing myself and my career in science. Throughout my scientific life, my interests have evolved from initially trying to understand the physical and chemical properties of small molecules toward unraveling biological systems. To that end, I now apply biophysical, biochemical and chemistry tools. Along my journey, I developed and applied nuclear magnetic resonance (NMR) spectroscopy methods to figure out how proteins work at the atomic level and this voyage took me from Germany, where I earned degrees in Physics and Chemistry, to the UK and back to Germany, finally dropping anchor in the USA, where I have led research programs at both the National Institutes of Health and the University of Pittsburgh. I am now the UPMC Rosalind Franklin Professor and Chair of the Department of Structural Biology, University of Pittsburgh School of Medicine, a Professor of Bioengineering, Swanson School of Engineering, and a Professor of Chemistry, Dietrich School of Arts and Sciences, University of Pittsburgh. © International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany, part of Springer Nature 2021.

Entities:  

Year:  2021        PMID: 35059003      PMCID: PMC8724357          DOI: 10.1007/s12551-021-00886-7

Source DB:  PubMed          Journal:  Biophys Rev        ISSN: 1867-2450


  34 in total

1.  Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy.

Authors:  G M Clore; A M Gronenborn
Journal:  Science       Date:  1991-06-07       Impact factor: 47.728

2.  Assessing the Structures and Interactions of γD-Crystallin Deamidation Variants.

Authors:  Alex J Guseman; Matthew J Whitley; Jeremy J González; Nityam Rathi; Mikayla Ambarian; Angela M Gronenborn
Journal:  Structure       Date:  2020-12-01       Impact factor: 5.006

3.  Conformational Plasticity of the NNRTI-Binding Pocket in HIV-1 Reverse Transcriptase: A Fluorine Nuclear Magnetic Resonance Study.

Authors:  Naima G Sharaf; Rieko Ishima; Angela M Gronenborn
Journal:  Biochemistry       Date:  2016-07-11       Impact factor: 3.162

4.  (19)F Paramagnetic Relaxation Enhancement: A Valuable Tool for Distance Measurements in Proteins.

Authors:  Elena Matei; Angela M Gronenborn
Journal:  Angew Chem Int Ed Engl       Date:  2015-10-29       Impact factor: 15.336

5.  An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity.

Authors:  Troy C Krzysiak; Laurel Thomas; You-Jin Choi; Sylvain Auclair; Yiqi Qian; Shan Luan; Stephanie M Krasnow; Laura L Thomas; Leonardus M I Koharudin; Panayiotis V Benos; Daniel L Marks; Angela M Gronenborn; Gary Thomas
Journal:  Mol Cell       Date:  2018-11-08       Impact factor: 17.970

6.  19F Dynamic Nuclear Polarization at Fast Magic Angle Spinning for NMR of HIV-1 Capsid Protein Assemblies.

Authors:  Manman Lu; Mingzhang Wang; Ivan V Sergeyev; Caitlin M Quinn; Jochem Struppe; Melanie Rosay; Werner Maas; Angela M Gronenborn; Tatyana Polenova
Journal:  J Am Chem Soc       Date:  2019-04-01       Impact factor: 15.419

7.  Human βB2-Crystallin Forms a Face-en-Face Dimer in Solution: An Integrated NMR and SAXS Study.

Authors:  Zhaoyong Xi; Matthew J Whitley; Angela M Gronenborn
Journal:  Structure       Date:  2017-02-23       Impact factor: 5.006

8.  Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy.

Authors:  J G Omichinski; G M Clore; K Sakaguchi; E Appella; A M Gronenborn
Journal:  FEBS Lett       Date:  1991-11-04       Impact factor: 4.124

9.  The conformations of hirudin in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics.

Authors:  G M Clore; D K Sukumaran; M Nilges; J Zarbock; A M Gronenborn
Journal:  EMBO J       Date:  1987-02       Impact factor: 11.598

Review 10.  Integrative structural biology of HIV-1 capsid protein assemblies: combining experiment and computation.

Authors:  Juan R Perilla; Jodi A Hadden-Perilla; Angela M Gronenborn; Tatyana Polenova
Journal:  Curr Opin Virol       Date:  2021-04-23       Impact factor: 7.121

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