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Literature DB >> 3505888

Detecting genetic effects on lipoprotein phenotypes in baboons: a review of methods and preliminary findings.

J W MacCluer¹, C M Kammerer, J L VandeBerg, M L Cheng, G E Mott, H C McGill.

Abstract

Statistical methods for detecting the contribution of major genes to quantitative phenotypes have been widely applied in human family studies. Some of these methods are reviewed, and their application to analysis of an animal model for a human disease is described. Analysis of lipoprotein concentrations in pedigreed baboons provides evidence for genetic effects on specific lipoprotein components that have been associated with reduced susceptibility to atherosclerosis in humans.

Entities: Disease Species

Mesh：

Substances：

Year: 1987 PMID： 3505888 DOI： 10.1007/bf00057446

Source DB: PubMed Journal: Genetica ISSN： 0016-6707 Impact factor: 1.082

20 in total

1. Isolation and characterization of the major lipoprotein density classes of normal and diabetic baboon (Papio anubis) plasma.

Authors: D Bojanovski; P Alaupovic; J L Kelley; C Stout
Journal: Atherosclerosis Date: 1978-12 Impact factor: 5.162

2. LDL heterogeneity and atherosclerosis in nonhuman primates.

Authors: L L Rudel; M G Bond; B C Bullock
Journal: Ann N Y Acad Sci Date: 1985 Impact factor: 5.691

3. Genetic mediation of lipoprotein cholesterol and apoprotein concentrations in the baboon (Papio sp.).

Authors: B L Flow; G E Mott; J L Kelley
Journal: Atherosclerosis Date: 1982-05 Impact factor: 5.162

4. Genetic variation in serum low density lipoproteins and lipid levels in man.

Authors: K Berg; C Hames; G Dahlén; M H Frick; I Krishan
Journal: Proc Natl Acad Sci U S A Date: 1976-03 Impact factor: 11.205

5. Relationship between plasma lipid concentrations and coronary artery disease in 496 patients.

Authors: A M Gotto; G A Gorry; J R Thompson; J S Cole; R Trost; D Yeshurun; M E DeBakey
Journal: Circulation Date: 1977-11 Impact factor: 29.690

6. Plasma lipoproteins and coronary arteriography in subjects in the program on the surgical control of the hyperlipidemias. Preliminary report.

Authors: R B Moore; J M Long; J P Matts; K Amplatz; R L Varco; H Buchwald
Journal: Atherosclerosis Date: 1979-02 Impact factor: 5.162

7. Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.

Authors: C F Sing; J Davignon
Journal: Am J Hum Genet Date: 1985-03 Impact factor: 11.025

8. Study of the genetic transmission of hypercholesterolemia and hypertriglyceridemia in a 195 member kindred.

Authors: R C Elston; K K Namboodiri; C J Glueck; R Fallat; R Tsang; V Leuba
Journal: Ann Hum Genet Date: 1975-07 Impact factor: 1.670

9. Relationship of lipoprotein cholesterol concentrations to experimental atherosclerosis in baboons.

Authors: H C McGill; C A McMahan; A W Kruski; G E Mott
Journal: Arteriosclerosis Date: 1981 Jan-Feb

10. Genetic analysis of the Stanford LRC family study data. II. Structured exploratory data analysis of lipids and lipoproteins.

Authors: S Karlin; P T Williams; W L Haskell; P D Wood
Journal: Am J Epidemiol Date: 1981-03 Impact factor: 4.897

4 in total

4. Baboon carboxylesterases 1 and 2: sequences, structures and phylogenetic relationships with human and other primate carboxylesterases.

Authors: Roger S Holmes; Jeremy P Glenn; John L VandeBerg; Laura A Cox
Journal: J Med Primatol Date: 2009-02 Impact factor: 0.667