Efficient Valorization of Sugarcane Bagasse into Furfurylamine in Benign Deep Eutectic Solvent ChCl:Gly-Water.

Recently, highly efficient production of valuable furan-based chemicals from available and renewable lignocellulosic biomass has attracted more and more attention via a chemoenzymatic route in an environmentally friendly reaction system. In this work, the feasibility of chemoenzymatically catalyzing sugarcane bagasse into furfurylamine with heterogeneous catalyst and ω-transaminase biocatalyst was developed in the deep eutectic solvent (DES) ChCl:Gly-water. Sulfonated Al-Laubanite was firstly synthesized to catalyze sugarcane bagasse to furfural. SEM, BET, XRD, and FT-IR were used to characterize Al-Laubanite. Catalyst Al-Laubanite structure was significantly different from carrier laubanite. High furfural yield (60.9%) was achieved by catalyzing sugarcane bagasse in 20 min at 170 ℃ and pH 1.0 by Al-Laubanite (2.4 wt%) in the presence of ChCl:Gly (20 wt%). Potential catalytic mechanism was proposed under the optimized catalytic condition. In addition, one recombinant E. coli CV harboring ω-transaminase could completely transform biomass-derived furfural to furfurylamine at 40 °C and pH 7.5 using L-alanine as amine donor in ChCl:Gly-water (20:80, wt:wt). This established chemoenzymatic cascade reaction strategy was successfully utilized for valorization of biomass into furan-based chemicals in the benign ChCl:Gly-water system.