Literature DB >> 35046595

The biological clean-ups that could combat age-related disease.

Elie Dolgin.   

Abstract

Entities:  

Keywords:  Ageing; Biotechnology; Drug discovery

Mesh：

Substances：

Year:  2022        PMID： 35046595     DOI： 10.1038/d41586-022-00075-w

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  9 in total

1.  AUTACs: Cargo-Specific Degraders Using Selective Autophagy.

Authors:  Daiki Takahashi; Jun Moriyama; Tomoe Nakamura; Erika Miki; Eriko Takahashi; Ayami Sato; Takaaki Akaike; Kaori Itto-Nakama; Hirokazu Arimoto
Journal:  Mol Cell       Date:  2019-10-09       Impact factor: 17.970

2.  The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance.

Authors:  Mingjun Shi; Jenny Maique; Joy Shaffer; Taylor Davidson; Salwa Sebti; Álvaro F Fernández; Zhongju Zou; Shirley Yan; Beth Levine; Orson W Moe; Ming Chang Hu
Journal:  FASEB J       Date:  2020-01-05       Impact factor: 5.191

3.  Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.

Authors:  Zhaoyang Li; Cen Wang; Ziying Wang; Chenggang Zhu; Jie Li; Tian Sha; Lixiang Ma; Chao Gao; Yi Yang; Yimin Sun; Jian Wang; Xiaoli Sun; Chenqi Lu; Marian Difiglia; Yanai Mei; Chen Ding; Shouqing Luo; Yongjun Dang; Yu Ding; Yiyan Fei; Boxun Lu
Journal:  Nature       Date:  2019-10-30       Impact factor: 49.962

4.  Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.

Authors:  Mathieu Bourdenx; Adrián Martín-Segura; Aurora Scrivo; Jose A Rodriguez-Navarro; Susmita Kaushik; Inmaculada Tasset; Antonio Diaz; Nadia J Storm; Qisheng Xin; Yves R Juste; Erica Stevenson; Enrique Luengo; Cristina C Clement; Se Joon Choi; Nevan J Krogan; Eugene V Mosharov; Laura Santambrogio; Fiona Grueninger; Ludovic Collin; Danielle L Swaney; David Sulzer; Evripidis Gavathiotis; Ana Maria Cuervo
Journal:  Cell       Date:  2021-04-22       Impact factor: 66.850

5.  A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.

Authors:  Altea Rocchi; Soh Yamamoto; Tabitha Ting; Yuying Fan; Katherine Sadleir; Yigang Wang; Weiran Zhang; Sui Huang; Beth Levine; Robert Vassar; Congcong He
Journal:  PLoS Genet       Date:  2017-08-14       Impact factor: 5.917

6.  Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Authors:  Álvaro F Fernández; Salwa Sebti; Yongjie Wei; Zhongju Zou; Mingjun Shi; Kathryn L McMillan; Congcong He; Tabitha Ting; Yang Liu; Wei-Chung Chiang; Denise K Marciano; Gabriele G Schiattarella; Govind Bhagat; Orson W Moe; Ming Chang Hu; Beth Levine
Journal:  Nature       Date:  2018-05-30       Impact factor: 49.962

7.  Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

Authors:  Farah H Siddiqi; Fiona M Menzies; Ana Lopez; Eleanna Stamatakou; Cansu Karabiyik; Rodrigo Ureshino; Thomas Ricketts; Maria Jimenez-Sanchez; Miguel Angel Esteban; Liangxue Lai; Micky D Tortorella; Zhiwei Luo; Hao Liu; Emmanouil Metzakopian; Hugo J R Fernandes; Andrew Bassett; Eric Karran; Bruce L Miller; Angeleen Fleming; David C Rubinsztein
Journal:  Nat Commun       Date:  2019-04-18       Impact factor: 14.919

8.  Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives.

Authors:  Jaime Anguiano; Thomas P Garner; Murugesan Mahalingam; Bhaskar C Das; Evripidis Gavathiotis; Ana Maria Cuervo
Journal:  Nat Chem Biol       Date:  2013-04-14       Impact factor: 15.040

9.  Chaperone-mediated autophagy sustains haematopoietic stem-cell function.

Authors:  Shuxian Dong; Qian Wang; Yun-Ruei Kao; Antonio Diaz; Inmaculada Tasset; Susmita Kaushik; Victor Thiruthuvanathan; Aliona Zintiridou; Edward Nieves; Monika Dzieciatkowska; Julie A Reisz; Evripidis Gavathiotis; Angelo D'Alessandro; Britta Will; Ana Maria Cuervo
Journal:  Nature       Date:  2021-01-13       Impact factor: 49.962
  9 in total

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