Literature DB >> 3503918

Hypotensive effect of bromocriptine in glaucomatous eyes.

O Geyer1, D Robinson, M Lazar.   

Abstract

The effect of a single oral dose of 2.5 mg bromocriptine on intraocular pressure in 20 glaucoma patients is reported. Intraocular pressure was significantly reduced (31%), the maximal response being after 4-6 hours. A decrease in blood pressure was also noticed, maximal reduction (5%) at 4 hours. Three patients experienced nausea and dizziness. Possibly the reducing effect of bromocriptine on intraocular pressure is mediated by the stimulation of intraocular dopamine receptors (DA2).

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Year:  1987        PMID: 3503918     DOI: 10.1089/jop.1987.3.291

Source DB:  PubMed          Journal:  J Ocul Pharmacol        ISSN: 8756-3320


  5 in total

1.  A comparison of the ocular hypotensive effect of 0.025% bromocriptine and 0.25% timolol eye drops in normal human volunteers.

Authors:  M R al-Sereiti; R L Coakes; D P O'Sullivan; P Turner
Journal:  Br J Clin Pharmacol       Date:  1989-10       Impact factor: 4.335

2.  The effect of a single oral dose of pergolide on intraocular pressure and pupil diameter.

Authors:  M R al-Sereiti; R F Quik; P Turner
Journal:  Br J Clin Pharmacol       Date:  1989-09       Impact factor: 4.335

3.  The effects of lisuride, terguride and bromocriptine on intraocular pressure (IOP).

Authors:  M R Al-Sereiti; P Turner
Journal:  Br J Clin Pharmacol       Date:  1989-02       Impact factor: 4.335

4.  Elevated prolactin levels in human aqueous humor of patients with anterior uveitis.

Authors:  U Pleyer; D Gupta; E G Weidle; W Lisch; M Zierhut; H J Thiel
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1991       Impact factor: 3.117

5.  Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation.

Authors:  Chiara Bianca Maria Platania; Salvatore Salomone; Gian Marco Leggio; Filippo Drago; Claudio Bucolo
Journal:  PLoS One       Date:  2012-09-06       Impact factor: 3.240

  5 in total

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