Literature DB >> 35035757

Diagnosis and treatment of carotid body tumors.

Junjie Liu1,2, Hong Mu3, Weidong Zhang1.   

Abstract

PURPOSE: To investigate the clinical diagnosis, treatment, and complication prevention of carotid body tumors (CBTs).
METHODS: The medical records of 24 patients with CBTs treated in the Department of Oral and Maxillofacial Surgery in Shandong Provincial Hospital Affiliated to Shandong First Medical University from 1999 to 2014 were reviewed. All the patients had unilateral CBTs and underwent preoperative B-mode ultrasound. Before surgery, CBT diagnosis was confirmed by digital subtraction angiography (DSA) in 8 patients, magnetic resonance imaging (MRI) in 9 patients, and computed tomography angiography (CTA) in 11 patients. All the patients had surgical intervention and preoperative Matas test. The retrograde stump pressure in the internal carotid artery was monitored in all the cases during surgery. Transcranial Doppler (TCD) inspection was performed on all patients before and during surgery. Simple tumor resection was performed in 8 patients, and excision of both the tumor and external carotid artery was performed in 11 cases. Five patients received intraluminal shunt after tumor resection and partial removal of internal, external, and common carotid arteries.
RESULTS: The diagnostic accuracy of B-mode ultrasound, DSA, MRI, and CTA was 75%, 100%, 88.9%, and 90.9%, respectively. In the enrolled 24 patients, tumors were completely removed with no postoperative death, hemiplegia, or blindness. There were 4 cases of transient hypoglossal nerve palsy and 1 case of transient vagus nerve involvement after surgery, which were recovered after 4-8 months of follow-up. No recurrence was found in the included patients during the followed-up, varied from 3 months to 4 years. B-mode ultrasound examination can be used as a preliminary screening method. DSA, CTA, and MRI are all effective diagnostic tools for CBTs. Among them, the diagnostic coincidence rate of DSA is 100%, making it the most effective means of inspection. Surgical resection is the first choice for the treatment of CBT patients who are willing to undergo surgery.
CONCLUSIONS: Preoperative routine Matas test can improve the brain tolerance of patients with carotid artery occlusion, preoperative, and intraoperative TCD monitoring are beneficial to understand the intracranial circulation in the circle of Willis. Intraoperative monitoring of residual arterial pressure and intraluminal shunt can prevent or significantly reduce the incidence of serious postoperative complications. AJTR
Copyright © 2021.

Entities:  

Keywords:  Carotid body tumor; imageological examination; surgical treatment

Year:  2021        PMID: 35035757      PMCID: PMC8748146     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   4.060


  43 in total

1.  Carotid body tumor (chemodectoma). Clinicopathologic analysis of ninety cases.

Authors:  W R Shamblin; W H ReMine; S G Sheps; E G Harrison
Journal:  Am J Surg       Date:  1971-12       Impact factor: 2.565

Review 2.  Overt and Subclinical Baroreflex Dysfunction After Bilateral Carotid Body Tumor Resection: Pathophysiology, Diagnosis, and Implications for Management.

Authors:  Michael G Z Ghali; Visish M Srinivasan; Ehab Hanna; Franco DeMonte
Journal:  World Neurosurg       Date:  2017-02-27       Impact factor: 2.104

3.  Clinical Outcome of Carotid Body Paraganglioma Management: A Review of 10-Year Experience.

Authors:  Ahmed Elsayed Fathalla; Mohammad Ahmad Elalfy
Journal:  J Oncol       Date:  2020-07-20       Impact factor: 4.375

Review 4.  [Dignity of carotid body tumors. Review of the literature and clinical experiences].

Authors:  D Grotemeyer; S M Loghmanieh; S Pourhassan; T A Sagban; F Iskandar; P Reinecke; W Sandmann
Journal:  Chirurg       Date:  2009-09       Impact factor: 0.955

Review 5.  Carotid and vertebral artery disease.

Authors:  Maxim Mokin; Travis M Dumont; Tareq Kass-Hout; Elad I Levy
Journal:  Prim Care       Date:  2012-12-08       Impact factor: 2.907

6.  Surgical Management of Bilateral Carotid Body Tumors.

Authors:  Luis O Bobadilla-Rosado; Ramon Garcia-Alva; Javier E Anaya-Ayala; Cynthia Peralta-Vazquez; Kemberly Hernandez-Sotelo; Lizeth Luna; Cesar Cuen-Ojeda; Carlos A Hinojosa
Journal:  Ann Vasc Surg       Date:  2019-01-24       Impact factor: 1.466

7.  Assessment of carotid artery atherosclerotic disease by using three-dimensional fast black-blood MR imaging: comparison with DSA.

Authors:  Huilin Zhao; Jinnan Wang; Xiaosheng Liu; Xihai Zhao; Daniel S Hippe; Ye Cao; Jieqing Wan; Chun Yuan; Jianrong Xu
Journal:  Radiology       Date:  2014-10-03       Impact factor: 11.105

8.  Carotid body tumor excisions: adverse outcomes of adding carotid endarterectomy.

Authors:  J Gary Maxwell; Samuel W Jones; Ewain Wilson; Cyrus A Kotwall; Tana Hall; Sue Hamann; Carla C Brinker
Journal:  J Am Coll Surg       Date:  2004-01       Impact factor: 6.113

9.  Outcome of Surgical Treatment for Carotid Body Tumors in Different Shambling Type Without Preoperative Embolization: A Single-Center Retrospective Study.

Authors:  Tonglei Han; Shiying Wang; Xiaolong Wei; Yongfu Xie; Yudong Sun; Huiying Sun; Jiang Zhu; Yani Wu; Jian Zhou; Zhiqing Zhao; Zaiping Jing
Journal:  Ann Vasc Surg       Date:  2019-10-15       Impact factor: 1.466

10.  The Outcome of Multidisciplinary Management of Carotid Body Tumors: Retrospective Cohort Study.

Authors:  Ahmed Gaber Hassanein; Kamal A-A M Hassanein; Khalid Nasser Fadle; Ahmed Seif Al-Eslam; Fahd Nasser Al Qahtani
Journal:  J Maxillofac Oral Surg       Date:  2018-12-03
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