Literature DB >> 35035678

Potential effects of COVID-19 on reproductive health: a mini review.

Xiao-Dong Mao1, Kang-Sheng Liu2, Yan-Ping Yao3, Zhi-Rong Xu4.   

Abstract

Coronavirus disease 2019 (COVID-19) is now a major public health problem worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is extremely strong. One major target of the virus is the lung, which can lead to death due to the development of respiratory distress syndrome and even multiple system organ failure. The possible pathophysiology by which SARS-CoV-2 affects the object is by way of the receptor, angiotensin-converting enzyme 2 (ACE2). From the study of the viral structure and infection mechanisms, researchers have discovered that the ACE2 acts as a receptor for SARS-CoV-2. According to previous studies, ACE2 is one of the key enzymes in the RAS system. Physiological functions can be found in angiosarcomas and in the kidney, liver, intestine and so on. Whether SARS-CoV-2 infection leads to male fertility impairment has recently received attention. Nevertheless, the association between SARS-CoV-2 infection and reproductive health is currently poorly understood. Using key words including "SARS-CoV-2", "reproductive health", "ACE2" and "2019-nCoV", we retrieved original articles and reviews from the PubMed and WEB OF SCI databases published before December 16, 2020 and performed a thorough review of them. Compared with females, we discovered that infected person with SARS-CoV-2 was higher in males. Men who were infected with SARS-CoV-2 may be easy to suffer from impaired reproductive health. These investigations would help for a comprehensive grasp of the relationship between SARS-CoV-2 infection and reproductive health. AJTR
Copyright © 2021.

Entities:  

Keywords:  2019-nCoV; ACE2; SARS-CoV-2; reproductive health; sperm

Year:  2021        PMID: 35035678      PMCID: PMC8748173     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   4.060


  40 in total

1.  Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary.

Authors:  Fernando M Reis; Daniela R Bouissou; Virginia M Pereira; Aroldo F Camargos; Adelina M dos Reis; Robson A Santos
Journal:  Fertil Steril       Date:  2010-08-01       Impact factor: 7.329

2.  The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis.

Authors:  Gabrielle C Douglas; Moira K O'Bryan; Mark P Hedger; David K L Lee; Michael A Yarski; A Ian Smith; Rebecca A Lew
Journal:  Endocrinology       Date:  2004-07-01       Impact factor: 4.736

3.  TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.

Authors:  Adeline Heurich; Heike Hofmann-Winkler; Stefanie Gierer; Thomas Liepold; Olaf Jahn; Stefan Pöhlmann
Journal:  J Virol       Date:  2013-11-13       Impact factor: 5.103

4.  Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications.

Authors:  Ming Yang; Shuo Chen; Bo Huang; Jing-Min Zhong; Hua Su; Ya-Jun Chen; Qin Cao; Lin Ma; Jun He; Xue-Fei Li; Xiang Li; Jun-Jie Zhou; Jun Fan; Dan-Ju Luo; Xiao-Na Chang; Knarik Arkun; Ming Zhou; Xiu Nie
Journal:  Eur Urol Focus       Date:  2020-05-31

5.  Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19.

Authors:  Huilan Zhang; Peng Zhou; Yanqiu Wei; Huihui Yue; Yi Wang; Ming Hu; Shu Zhang; Tanze Cao; Chengqing Yang; Ming Li; Guangyun Guo; Xianxiang Chen; Ying Chen; Mei Lei; Huiguo Liu; Jianping Zhao; Peng Peng; Cong-Yi Wang; Ronghui Du
Journal:  Ann Intern Med       Date:  2020-03-12       Impact factor: 25.391

Review 6.  Pathogenesis of COVID-19 and the quality control of nucleic acid detection.

Authors:  Xiao-Dong Mao; Taiping Li; Zhirong Xu; Kangsheng Liu
Journal:  Biochem Biophys Res Commun       Date:  2021-01-01       Impact factor: 3.575

7.  Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome.

Authors:  Shell F Wong; Kam M Chow; Tse N Leung; Wai F Ng; Tak K Ng; Chi C Shek; Pak C Ng; Pansy W Y Lam; Lau C Ho; William W K To; Sik T Lai; Wing W Yan; Peggy Y H Tan
Journal:  Am J Obstet Gynecol       Date:  2004-07       Impact factor: 8.661

8.  scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells.

Authors:  Zhengpin Wang; Xiaojiang Xu
Journal:  Cells       Date:  2020-04-09       Impact factor: 6.600

9.  Assessment of SARS-CoV-2 in human semen-a cohort study.

Authors:  Nora Holtmann; Philippos Edimiris; Marcel Andree; Cornelius Doehmen; Dunja Baston-Buest; Ortwin Adams; Jan-Steffen Kruessel; Alexandra Petra Bielfeld
Journal:  Fertil Steril       Date:  2020-05-29       Impact factor: 7.490

Review 10.  Potential mechanisms of SARS-CoV-2 action on male gonadal function and fertility: Current status and future prospects.

Authors:  Abdolreza Haghpanah; Fatemeh Masjedi; Saeed Alborzi; Alireza Hosseinpour; Anahita Dehghani; Leila Malekmakan; Jamshid Roozbeh
Journal:  Andrologia       Date:  2020-10-27       Impact factor: 2.532

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  1 in total

1.  Cellular and Molecular Mechanisms of In Vivo and In Vitro SARS-CoV-2 Infection: A Lesson from Human Sperm.

Authors:  Alice Luddi; Francesca Paola Luongo; Filippo Dragoni; Lia Fiaschi; Ilaria Vicenti; Pietro Lupetti; Mariangela Gentile; Eugenio Paccagnini; Alesandro Haxhiu; Rosetta Ponchia; Laura Governini; Maurizio Zazzi; Paola Piomboni
Journal:  Cells       Date:  2022-08-24       Impact factor: 7.666

  1 in total

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