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Literature DB >> 35033503

Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors.

Sharon Moore¹, Ami Radunskaya², Elizabeth Zollinger³, Kathleen A Grant⁴, Steven Gonzales⁴, Nicole A R Walter⁴, Erich J Baker¹.

Abstract

We present a blood ethanol concentration compartment model which utilizes an animal's ethanol intake, food intake, and weight to predict the animal's blood ethanol concentration at any given time. By incorporating the food digestion process into the model we can predict blood ethanol concentration levels over time for a variety of drinking and eating scenarios. The model is calibrated and validated using data from cohorts of male monkeys, and is able to capture blood ethanol concentration kinetics of the monkeys from a variety of drinking behavior classifications.

Entities: Chemical

Keywords: Alcohol use disorder; Differential equations; Drinking classification; Mathematical modeling

Mesh：

Substances：

Year: 2022 PMID： 35033503 PMCID： PMC8918017 DOI： 10.1016/j.mbs.2022.108778

Source DB: PubMed Journal: Math Biosci ISSN： 0025-5564 Impact factor: 3.935

32 in total

1. Discriminative Stimulus Effects and Metabolism of Ethanol in Rhesus Monkeys.

Authors: Daicia C Allen; Kathleen A Grant
Journal: Alcohol Clin Exp Res Date: 2019-07-16 Impact factor: 3.455

2. Voluntary Chronic Heavy Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity.

Authors: Arianna M Kahler-Quesada; Kathleen A Grant; Nicole A R Walter; Natali Newman; Matthew R Allen; David B Burr; Adam J Branscum; Gianni F Maddalozzo; Russell T Turner; Urszula T Iwaniec
Journal: Alcohol Clin Exp Res Date: 2019-10-17 Impact factor: 3.455

Review 3. Studies using macaque monkeys to address excessive alcohol drinking and stress interactions.

Authors: Vanessa A Jimenez; Kathleen A Grant
Journal: Neuropharmacology Date: 2017-03-24 Impact factor: 5.250

4. On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome.

Authors: Ovidiu D Iancu; Alexander Colville; Nicole A R Walter; Priscila Darakjian; Denesa L Oberbeck; James B Daunais; Christina L Zheng; Robert P Searles; Shannon K McWeeney; Kathleen A Grant; Robert Hitzemann
Journal: Addict Biol Date: 2017-02-28 Impact factor: 4.280

5. Chronic alcohol self-administration in monkeys shows long-term quantity/frequency categorical stability.

Authors: Erich J Baker; Jonathan Farro; Steven Gonzales; Christa Helms; Kathleen A Grant
Journal: Alcohol Clin Exp Res Date: 2014-11 Impact factor: 3.455

6. Induction and maintenance of ethanol self-administration in cynomolgus monkeys (Macaca fascicularis): long-term characterization of sex and individual differences.

Authors: J A Vivian; H L Green; J E Young; L S Majerksy; B W Thomas; C A Shively; J R Tobin; M A Nader; K A Grant
Journal: Alcohol Clin Exp Res Date: 2001-08 Impact factor: 3.455

Pairing food and drink: A physiological model of blood ethanol levels for a variety of drinking behaviors.

1. Discriminative Stimulus Effects and Metabolism of Ethanol in Rhesus Monkeys.

2. Voluntary Chronic Heavy Alcohol Consumption in Male Rhesus Macaques Suppresses Cancellous Bone Formation and Increases Bone Marrow Adiposity.

Review 3. Studies using macaque monkeys to address excessive alcohol drinking and stress interactions.

4. On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome.

5. Chronic alcohol self-administration in monkeys shows long-term quantity/frequency categorical stability.

6. Induction and maintenance of ethanol self-administration in cynomolgus monkeys (Macaca fascicularis): long-term characterization of sex and individual differences.

7. Uncertainty in estimating blood ethanol concentrations by analysis of vitreous humour.

8. Physiologically based pharmacokinetic (PBPK) models for ethanol.

9. Measurement of Blood Volume in Adult Rhesus Macaques (Macaca mulatta).

10. Monkey alcohol tissue research resource: banking tissues for alcohol research.

1. Impact of putamen inhibition by DREADDs on schedule-induced drinking in rhesus monkeys.