| Literature DB >> 3503115 |
A J Flach1, J S Peterson, M E Donahue.
Abstract
Waterloading tests are used in rabbits to screen potentially useful ocular hypotensive drugs. The present study examines the ocular hypertensive response following oral, intravenous and intraperitoneal administration of water in conscious Dutch belt pigmented rabbits. All methods of waterloading were well tolerated by rabbits. However, intraperitoneal waterloading provided an ocular hypertensive effect of longer duration than either oral or intravenous waterloading.Entities:
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Year: 1986 PMID： 3503115 DOI： 10.1089/jop.1986.2.313
Source DB: PubMed Journal: J Ocul Pharmacol ISSN： 8756-3320