Literature DB >> 35028138

Cerebral calcium embolism.

Pedro Asensi Cantó1, Jürgen Solís Ruíz1, Pilar Lloret Madrid1, Santiago Bonanad Boix1.   

Abstract

A new-onset neurological deficit after calcified aortic valve replacement and an hyperdense image on the computed tomography raised suspicion of an stroke of unusual etiology.
© 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Entities:  

Keywords:  anticoagulation; calcium embolism; stroke

Year:  2022        PMID: 35028138      PMCID: PMC8741867          DOI: 10.1002/ccr3.4962

Source DB:  PubMed          Journal:  Clin Case Rep        ISSN: 2050-0904


CASE DESCRIPTION

A 59‐year‐old man with aortic valve calcification, which conditioned severe stenosis, was admitted to the recovery room after mechanical aortic valve replacement. Sedation withdrawal revealed a right‐side hemiparesis and an inability to obey verbal commands. Urgent computed tomography showed mild hypoattenuation and loss of gray‐white differentiation in the left middle cerebral artery territory (Figure 1, left, arrowheads) . A calcium density image (Figure 1, left, arrow) , concordant with calcified valve migration, was found in M1 segment of the left middle cerebral artery. Given the potential hemorrhagic transformation of the ischemic area produced by a high severity stroke,1 the risks of therapeutic anticoagulation were deemed greater than its advantages in terms of preventing thrombus formation on the mechanical valve. Therefore, only prophylactic‐dose heparin was prescribed. In the course of the following days, the patient slipped into a coma and developed a malignant ischemic stroke (Figure 1, right) . The limitation of therapeutic effort was prioritized.
FIGURE 1

Computed tomagraphy on the onset of symptoms (left) and 5 days later (right)

Computed tomagraphy on the onset of symptoms (left) and 5 days later (right) Calcium embolism is a rare cause of stroke, but it is a well‐described complication after transcatheter aortic valve implantation. This concern has led to the development and implementation in the clinical practice of different embolic protection devices. Once the calcium embolus migrates into brain vasculature, anticoagulation management of these patients is controversial and requires a case‐by‐case assessment.

AUTHOR CONTRIBUTIONS

Asensi Cantó P. wrote the case report. Solís Ruíz J. and Lloret Madrid P. suggested improvements. Bonanad Boix S. was the caregiver of the patient, and revised the manuscript and suggested final changes.

CONSENT

Patient's family, as legally authorized representative, gave informed consent for the publication of this case report.
  2 in total

Review 1.  Hemorrhagic Transformation in Ischemic Stroke and the Role of Inflammation.

Authors:  Elena Spronk; Gina Sykes; Sarina Falcione; Danielle Munsterman; Twinkle Joy; Joseph Kamtchum-Tatuene; Glen C Jickling
Journal:  Front Neurol       Date:  2021-05-14       Impact factor: 4.003

Review 2.  Cerebrovascular Events After Transcatheter Aortic Valve Implantation.

Authors:  German Armijo; Luis Nombela-Franco; Gabriela Tirado-Conte
Journal:  Front Cardiovasc Med       Date:  2018-07-31
  2 in total

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