Literature DB >> 35027536

Correction: Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine.

Xuemei He1,2, Weiqi Hong1, Jingyun Yang1, Hong Lei1, Tianqi Lu1, Cai He1, Zhenfei Bi1, Xiangyu Pan1, Yu Liu1, Lunzhi Dai1, Wei Wang1, Canhua Huang1, Hongxin Deng1, Xiawei Wei3.   

Abstract

Entities:  

Year:  2022        PMID: 35027536      PMCID: PMC8758697          DOI: 10.1038/s41392-021-00862-3

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN: 2059-3635


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Correction to: Sig Transduct Target Therapy 10.1038/s41392-021-00688-z, published online 14 July 2021 After online publication of the article[1], the authors noticed one inadvertent mistake in Fig. 5a that needs to be corrected. In detail, the pathological picture of PBS group in Fig. 5a is inadvertently duplicated as the image of PBS group in Fig. 7b in the main text. This duplication is a result of errors in figure assembly, and the correct Fig. 5 is provided as follows. The key findings of the article are not affected by these corrections.
Fig. 5

PSLs ameliorate ConA-induced ALI and LPS-induced lung injury. a Mice were intravenously injected with 12 mg/kg ConA, followed by treatment with PBS, PCLs, or PSLs. Representative images of liver histopathology with H&E staining in each group. Scale bar represents 200 μm. b–d Quantitative analysis of necrosis area (b), TUNEL-positive cells (c), and serum ALT and AST levels (d) in mice with PBS, PCLs, or PSLs treatment. n = 5. e Survival of 25 mg/kg ConA-injected mice treated with PBS, PCLs, and PSLs. n = 10. f, g The levels of IL-6, IFN-γ, and TNF-α in serum (f) and IL-10, HGF in hepatic tissues (g) were determined by ELISA. n = 3~5 in each group. h Representative images of lung histopathology 72 h after LPS administration. Scale bar represents 200 μm. i Histopathology score of lung sections in each group. n = 5 in each group. Data are represented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001

PSLs ameliorate ConA-induced ALI and LPS-induced lung injury. a Mice were intravenously injected with 12 mg/kg ConA, followed by treatment with PBS, PCLs, or PSLs. Representative images of liver histopathology with H&E staining in each group. Scale bar represents 200 μm. b–d Quantitative analysis of necrosis area (b), TUNEL-positive cells (c), and serum ALT and AST levels (d) in mice with PBS, PCLs, or PSLs treatment. n = 5. e Survival of 25 mg/kg ConA-injected mice treated with PBS, PCLs, and PSLs. n = 10. f, g The levels of IL-6, IFN-γ, and TNF-α in serum (f) and IL-10, HGF in hepatic tissues (g) were determined by ELISA. n = 3~5 in each group. h Representative images of lung histopathology 72 h after LPS administration. Scale bar represents 200 μm. i Histopathology score of lung sections in each group. n = 5 in each group. Data are represented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001
  1 in total

1.  Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine.

Authors:  Xuemei He; Weiqi Hong; Jingyun Yang; Hong Lei; Tianqi Lu; Cai He; Zhenfei Bi; Xiangyu Pan; Yu Liu; Lunzhi Dai; Wei Wang; Canhua Huang; Hongxin Deng; Xiawei Wei
Journal:  Signal Transduct Target Ther       Date:  2021-07-14
  1 in total

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