Sumit Randhir Singh1, Deepika C Parameswarappa2, Supriya Arora3, Dmitrii S Maltsev4, Niroj Kumar Sahoo5, Alexei N Kulikov4, Claudio Iovino6, Filippo Tatti7, Ramesh Venkatesh8, Nikitha Gurram Reddy8, Ram Snehith Pulipaka8, Enrico Peiretti7, Jay Chhablani9. 1. Jacobs Retina Center at Shiley Eye Center, University of California, San Diego, La Jolla, CA, USA. 2. Smt Kanuri Santhamma Center for Vitreo-Retina Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India. 3. Division of Ophthalmology, Department of Surgery, Princess Margaret Hospital, Nassau, Bahamas. 4. Department of Ophthalmology, Military Medical Academy, St Petersburg, Russian Federation. 5. Department of Retina and Vitreous, L V Prasad Eye Institute, Vijayawada, India. 6. Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, Naples, Italy. 7. Department of Surgical Sciences, Eye Clinic, University of Cagliari, Cagliari, Italy. 8. Department of Retina and Vitreous, Narayana Nethralaya, Bengaluru, India. 9. Department of Ophthalmology, University of Pittsburgh Eye and Ear Institute, Pittsburgh, PA, USA. jay.chhablani@gmail.com.
Abstract
PURPOSE: To report the disease pattern, progression and imaging characteristics in eyes with bilateral central serous chorioretinopathy (CSCR). METHODS: This was a retrospective case review of bilateral CSCR patients with active disease in at least one eye. Multimodal imaging including fundus photography, fundus autofluorescence, optical coherence tomography (OCT), fluorescein and indocyanine angiography (FA/ICGA) was done at baseline and follow-up visits. Disease classification was done using recently described classification criteria. The degree of asymmetry in the disease distribution pattern at baseline and disease progression during follow-up visit with a minimum duration of 12 months was studied. RESULTS: Among 103 CSCR patients, 36 patients (34.95%) with mean age of 53.6 ± 10.5 years had bilateral CSCR at baseline. Five patients (13.9%) had asymmetrical disease i.e. simple in one eye and complex in fellow eye. The remaining 31 patients had symmetric disease (simple, 2; complex 29). Mean duration of follow up was 17.58 ± 13.84 months. There was no significant difference between both eye parameters at last follow up (best corrected visual acuity, BCVA; central macular thickness, CMT; and subfoveal choroidal thickness, SFCT) (all p > 0.05). At last follow up, 22 eyes (2 simple and 20 complex) remained active whereas none of the eyes converted from simple to complex CSCR. CONCLUSION: Bilateral disease was more commonly seen with complex CSCR in contrast to simple CSCR. Moreover, disease distribution in complex CSCR had symmetric pattern if bilateral disease was present. None of the simple CSCR eyes converted to complex type.
PURPOSE: To report the disease pattern, progression and imaging characteristics in eyes with bilateral central serous chorioretinopathy (CSCR). METHODS: This was a retrospective case review of bilateral CSCR patients with active disease in at least one eye. Multimodal imaging including fundus photography, fundus autofluorescence, optical coherence tomography (OCT), fluorescein and indocyanine angiography (FA/ICGA) was done at baseline and follow-up visits. Disease classification was done using recently described classification criteria. The degree of asymmetry in the disease distribution pattern at baseline and disease progression during follow-up visit with a minimum duration of 12 months was studied. RESULTS: Among 103 CSCR patients, 36 patients (34.95%) with mean age of 53.6 ± 10.5 years had bilateral CSCR at baseline. Five patients (13.9%) had asymmetrical disease i.e. simple in one eye and complex in fellow eye. The remaining 31 patients had symmetric disease (simple, 2; complex 29). Mean duration of follow up was 17.58 ± 13.84 months. There was no significant difference between both eye parameters at last follow up (best corrected visual acuity, BCVA; central macular thickness, CMT; and subfoveal choroidal thickness, SFCT) (all p > 0.05). At last follow up, 22 eyes (2 simple and 20 complex) remained active whereas none of the eyes converted from simple to complex CSCR. CONCLUSION: Bilateral disease was more commonly seen with complex CSCR in contrast to simple CSCR. Moreover, disease distribution in complex CSCR had symmetric pattern if bilateral disease was present. None of the simple CSCR eyes converted to complex type.
Authors: Chandrakumar Balaratnasingam; K Bailey Freund; Anna M Tan; Sarah Mrejen; Alex P Hunyor; David J Keegan; Kunal K Dansingani; Pouya N Dayani; Irene A Barbazetto; David Sarraf; Lee M Jampol; Lawrence A Yannuzzi Journal: Ophthalmology Date: 2016-04-12 Impact factor: 12.079
Authors: Nichole Joachim; Johanna Maria Colijn; Annette Kifley; Kristine E Lee; Gabriëlle H S Buitendijk; Barbara E K Klein; Chelsea E Myers; Stacy M Meuer; Ava G Tan; Elizabeth G Holliday; John Attia; Gerald Liew; Sudha K Iyengar; Paulus T V M de Jong; Albert Hofman; Johannes R Vingerling; Paul Mitchell; Caroline C W Klaver; Ronald Klein; Jie Jin Wang Journal: Br J Ophthalmol Date: 2017-01-20 Impact factor: 4.638
Authors: John R Gonder; Valery M Walker; Martin Barbeau; Nancy Zaour; Bryan H Zachau; James R Hartje; Ruihong Li Journal: J Ophthalmol Date: 2014-03-26 Impact factor: 1.909
Authors: Daren Hanumunthadu; Anna C S Tan; Sumit Randhir Singh; Niroj Kumar Sahu; Jay Chhablani Journal: Indian J Ophthalmol Date: 2018-12 Impact factor: 1.848