Literature DB >> 3502245

Confirmation of the identities of inositol 1,3,4-trisphosphate and inositol 1,3,4,5-tetrakisphosphate by the use of one-dimensional and two-dimensional n.m.r. spectroscopy.

J C Lindon1, D J Baker, J M Williams, R F Irvine.   

Abstract

Multinuclear n.m.r. spectroscopy, including the use of two-dimensional methodology, was used to confirm the identity of inositol 1,3,4-triphosphate and its metabolic precursor inositol 1,3,4,5-tetrakisphosphate. The cyclohexane ring in each molecule exhibits a chair conformation with all phosphate groups occupying equatorial positions.

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Year:  1987        PMID： 3502245      PMCID： PMC1148037          DOI： 10.1042/bj2440591

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Myo-inositol phosphates obtained by alkaline hydrolysis of beef brain phosphoinositide.

Authors:  C GRADO; C E BALLOU
Journal:  J Biol Chem       Date:  1961-01       Impact factor: 5.157

Review 2.  The inositol phospholipids: a stereochemical view of biological activity.

Authors:  R Parthasarathy; F Eisenberg
Journal:  Biochem J       Date:  1986-04-15       Impact factor: 3.857

3.  The inositol tris/tetrakisphosphate pathway--demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues.

Authors:  R F Irvine; A J Letcher; J P Heslop; M J Berridge
Journal:  Nature       Date:  1986 Apr 17-23       Impact factor: 49.962

4.  Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices.

Authors:  I R Batty; S R Nahorski; R F Irvine
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

5.  1H, 13C and 31P n.m.r. spectra and molecular conformation of myo-inositol 1,4,5-triphosphate.

Authors:  J C Lindon; D J Baker; R D Farrant; J M Williams
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

6.  Nuclear magnetic resonance spectroscopic analysis of myo-inositol phosphates including inositol 1,3,4,5-tetrakisphosphate.

Authors:  S Cerdan; C A Hansen; R Johanson; T Inubushi; J R Williamson
Journal:  J Biol Chem       Date:  1986-11-05       Impact factor: 5.157

7.  Inositol trisphosphates in carbachol-stimulated rat parotid glands.

Authors:  R F Irvine; A J Letcher; D J Lander; C P Downes
Journal:  Biochem J       Date:  1984-10-01       Impact factor: 3.857

8.  Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+.

Authors:  R F Irvine; R M Moor
Journal:  Biochem J       Date:  1986-12-15       Impact factor: 3.857

9.  Specificity of inositol phosphate-stimulated Ca2+ mobilization from Swiss-mouse 3T3 cells.

Authors:  R F Irvine; A J Letcher; D J Lander; M J Berridge
Journal:  Biochem J       Date:  1986-11-15       Impact factor: 3.857

10.  Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands.

Authors:  R F Irvine; E E Anggård; A J Letcher; C P Downes
Journal:  Biochem J       Date:  1985-07-15       Impact factor: 3.857
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  2 in total

1.  Characterization of inositol 1,4,5-trisphosphate- and inositol 1,3,4,5-tetrakisphosphate-binding sites in rat cerebellum.

Authors:  R A Challiss; A L Willcocks; B Mulloy; B V Potter; S R Nahorski
Journal:  Biochem J       Date:  1991-03-15       Impact factor: 3.857

2.  Inositol phosphates from barley low-phytate grain mutants analysed by metal-dye detection HPLC and NMR.

Authors:  F Hatzack; F Hübel; W Zhang; P E Hansen; S K Rasmussen
Journal:  Biochem J       Date:  2001-03-01       Impact factor: 3.857
  2 in total

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