Konstantinos Perivoliotis1,2, Ioannis Baloyiannis3, George Tzovaras3. 1. Department of Surgery, General Hospital of Volos, Polymeri 134, Volos, 38222, Greece. kperi19@gmail.com. 2. Viopolis, University of Thessaly, Larissa, 41500, Greece. kperi19@gmail.com. 3. Department of Surgery, Mezourlo, University Hospital of Larissa, Larissa, 41110, Greece.
Abstract
INTRODUCTION: We conducted this meta-analysis, to compare cecorectal (CRA) and ileorectal anastomosis (IRA), regarding perioperative safety and efficacy, in patients submitted to colectomy for refractory slow transit constipation (STC). METHODS: This study followed the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA guidelines. To identify all eligible records, a systematic literature search in the electronic scholar databases (Medline, Scopus, Web of Science) was performed. RESULTS: Overall, 5 trials and 291 patients were included in this meta-analysis. Pooled comparisons confirmed the comparability of the two techniques regarding perioperative complications (p = 0.55). CRA was associated with a shorter operation (p = 0.0004) and hospitalization duration (p = 0.001). Although there was no difference in terms of gastrointestinal symptoms, functional outcomes, and patient satisfaction, CRA resulted in lower long-term Wexner scores (p < 0.0001). CONCLUSION: Due to several study limitations, further large-scale RCTs are required to verify the findings of the present meta-analysis.
INTRODUCTION: We conducted this meta-analysis, to compare cecorectal (CRA) and ileorectal anastomosis (IRA), regarding perioperative safety and efficacy, in patients submitted to colectomy for refractory slow transit constipation (STC). METHODS: This study followed the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA guidelines. To identify all eligible records, a systematic literature search in the electronic scholar databases (Medline, Scopus, Web of Science) was performed. RESULTS: Overall, 5 trials and 291 patients were included in this meta-analysis. Pooled comparisons confirmed the comparability of the two techniques regarding perioperative complications (p = 0.55). CRA was associated with a shorter operation (p = 0.0004) and hospitalization duration (p = 0.001). Although there was no difference in terms of gastrointestinal symptoms, functional outcomes, and patient satisfaction, CRA resulted in lower long-term Wexner scores (p < 0.0001). CONCLUSION: Due to several study limitations, further large-scale RCTs are required to verify the findings of the present meta-analysis.
Authors: Fan Li; Tao Fu; Weidong Tong; Anping Zhang; Chunxue Li; Yu Gao; Jin Song Wu; Baohua Liu Journal: Int J Colorectal Dis Date: 2014-09-25 Impact factor: 2.571
Authors: Imran Aziz; William E Whitehead; Olafur S Palsson; Hans Törnblom; Magnus Simrén Journal: Expert Rev Gastroenterol Hepatol Date: 2020-01-02 Impact factor: 3.869