Literature DB >> 35018142

COVID-19 outbreak in a long-term care facility in Kelowna, British Columbia after rollout of COVID-19 vaccine in March 2021.

Fatemeh Sabet1,2, Barbara Gauthier3, Muddassir Siddiqui3, Amanda Wilmer4, Natalie Prystajecky4,5, Pamela Rydings3, Michele Andrews3, Sue Pollock3,6.   

Abstract

BACKGROUND: In March 2021, a coronavirus disease 2019 (COVID-19) outbreak was declared at a large long-term care and short stay facility in British Columbia, Canada-well after introduction of the vaccination program in long-term care facilities that resulted in a dramatic decline in the number of outbreaks in this type of setting. The objective of this study is to provide the descriptive epidemiology of this outbreak, in the context of partial immunization of both residents and staff at the facility.
METHODS: The cases' information was extracted from a provincial information system (Panorama). Descriptive analysis was performed using Microsoft Excel and SAS. Outbreak management controls included, but were not limited to, asymptomatic testing and efforts to increase vaccination.
RESULTS: Twenty-six cases among the 241 resident and three cases among the 418 staff (corresponding to attack rates of 10% and less than 1%, respectively) were identified. The attack rate in residents was considerably lower than the average attack rate for COVID-19 outbreaks in long-term care facilities before the vaccine rollout. Seventeen resident cases were either partially or fully immunized. Four of the eight hospitalized cases and two of the three deceased cases were partially immunized. Seventeen cases were temporary stay residents. The three staff cases were not vaccinated. Ten cases were identified as part of asymptomatic testing.
CONCLUSION: Introduction of vaccination at facilities contributed to lower attack rates and higher numbers of asymptomatic cases in this outbreak. Screening asymptomatic individuals identified additional cases among vaccinated residents. Findings underscore the importance of achieving high vaccine coverage, including among temporary stay residents, to prevent virus introduction and subsequent unrecognized transmission opportunities.

Entities:  

Keywords:  COVID-19 vaccine; descriptive epidemiology; long-term care; outbreak

Year:  2021        PMID: 35018142      PMCID: PMC8699105          DOI: 10.14745/ccdr.v47i12a05

Source DB:  PubMed          Journal:  Can Commun Dis Rep        ISSN: 1188-4169


  13 in total

1.  Age-dependent Immune Response to the Biontech/Pfizer BNT162b2 Coronavirus Disease 2019 Vaccination.

Authors:  Lisa Müller; Marcel Andrée; Wiebke Moskorz; Ingo Drexler; Lara Walotka; Ramona Grothmann; Johannes Ptok; Jonas Hillebrandt; Anastasia Ritchie; Denise Rabl; Philipp Niklas Ostermann; Rebekka Robitzsch; Sandra Hauka; Andreas Walker; Christopher Menne; Ralf Grutza; Jörg Timm; Ortwin Adams; Heiner Schaal
Journal:  Clin Infect Dis       Date:  2021-12-06       Impact factor: 9.079

2.  Incident SARS-CoV-2 Infection among mRNA-Vaccinated and Unvaccinated Nursing Home Residents.

Authors:  Elizabeth M White; Xiaofei Yang; Carolyn Blackman; Richard A Feifer; Stefan Gravenstein; Vincent Mor
Journal:  N Engl J Med       Date:  2021-05-19       Impact factor: 91.245

3.  Vaccine Breakthrough Infections with SARS-CoV-2 Variants.

Authors:  Ezgi Hacisuleyman; Caryn Hale; Yuhki Saito; Nathalie E Blachere; Marissa Bergh; Erin G Conlon; Dennis J Schaefer-Babajew; Justin DaSilva; Frauke Muecksch; Christian Gaebler; Richard Lifton; Michel C Nussenzweig; Theodora Hatziioannou; Paul D Bieniasz; Robert B Darnell
Journal:  N Engl J Med       Date:  2021-04-21       Impact factor: 91.245

4.  Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks - Connecticut, December 2020-February 2021.

Authors:  Amadea Britton; Kara M Jacobs Slifka; Chris Edens; Srinivas Acharya Nanduri; Stephen M Bart; Nong Shang; Adora Harizaj; Jillian Armstrong; Kerui Xu; Hanna Y Ehrlich; Elizabeth Soda; Gordana Derado; Jennifer R Verani; Stephanie J Schrag; John A Jernigan; Vivian H Leung; Sunil Parikh
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2021-03-19       Impact factor: 17.586

5.  Multifaceted strategies for the control of COVID-19 outbreaks in long-term care facilities in Ontario, Canada.

Authors:  Thomas N Vilches; Shokoofeh Nourbakhsh; Kevin Zhang; Lyndon Juden-Kelly; Lauren E Cipriano; Joanne M Langley; Pratha Sah; Alison P Galvani; Seyed M Moghadas
Journal:  Prev Med       Date:  2021-04-17       Impact factor: 4.018

6.  Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals.

Authors:  Talia Kustin; Noam Harel; Doron Netzer; Shay Ben-Shachar; Uriah Finkel; Shay Perchik; Sheri Harari; Maayan Tahor; Itamar Caspi; Rachel Levy; Michael Leshchinsky; Shifra Ken Dror; Galit Bergerzon; Hala Gadban; Faten Gadban; Eti Eliassian; Orit Shimron; Loulou Saleh; Haim Ben-Zvi; Elena Keren Taraday; Doron Amichay; Anat Ben-Dor; Dana Sagas; Merav Strauss; Yonat Shemer Avni; Amit Huppert; Eldad Kepten; Ran D Balicer; Adi Stern
Journal:  Nat Med       Date:  2021-06-14       Impact factor: 53.440

7.  Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington.

Authors:  Temet M McMichael; Dustin W Currie; Shauna Clark; Sargis Pogosjans; Meagan Kay; Noah G Schwartz; James Lewis; Atar Baer; Vance Kawakami; Margaret D Lukoff; Jessica Ferro; Claire Brostrom-Smith; Thomas D Rea; Michael R Sayre; Francis X Riedo; Denny Russell; Brian Hiatt; Patricia Montgomery; Agam K Rao; Eric J Chow; Farrell Tobolowsky; Michael J Hughes; Ana C Bardossy; Lisa P Oakley; Jesica R Jacobs; Nimalie D Stone; Sujan C Reddy; John A Jernigan; Margaret A Honein; Thomas A Clark; Jeffrey S Duchin
Journal:  N Engl J Med       Date:  2020-03-27       Impact factor: 91.245

8.  Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers - Eight U.S. Locations, December 2020-March 2021.

Authors:  Mark G Thompson; Jefferey L Burgess; Allison L Naleway; Harmony L Tyner; Sarang K Yoon; Jennifer Meece; Lauren E W Olsho; Alberto J Caban-Martinez; Ashley Fowlkes; Karen Lutrick; Jennifer L Kuntz; Kayan Dunnigan; Marilyn J Odean; Kurt T Hegmann; Elisha Stefanski; Laura J Edwards; Natasha Schaefer-Solle; Lauren Grant; Katherine Ellingson; Holly C Groom; Tnelda Zunie; Matthew S Thiese; Lynn Ivacic; Meredith G Wesley; Julie Mayo Lamberte; Xiaoxiao Sun; Michael E Smith; Andrew L Phillips; Kimberly D Groover; Young M Yoo; Joe Gerald; Rachel T Brown; Meghan K Herring; Gregory Joseph; Shawn Beitel; Tyler C Morrill; Josephine Mak; Patrick Rivers; Katherine M Harris; Danielle R Hunt; Melissa L Arvay; Preeta Kutty; Alicia M Fry; Manjusha Gaglani
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2021-04-02       Impact factor: 17.586

9.  Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2.

Authors:  Dami A Collier; Isabella A T M Ferreira; Prasanti Kotagiri; Rawlings P Datir; Eleanor Y Lim; Emma Touizer; Bo Meng; Adam Abdullahi; Anne Elmer; Nathalie Kingston; Barbara Graves; Emma Le Gresley; Daniela Caputo; Laura Bergamaschi; Kenneth G C Smith; John R Bradley; Lourdes Ceron-Gutierrez; Paulina Cortes-Acevedo; Gabriela Barcenas-Morales; Michelle A Linterman; Laura E McCoy; Chris Davis; Emma Thomson; Paul A Lyons; Eoin McKinney; Rainer Doffinger; Mark Wills; Ravindra K Gupta
Journal:  Nature       Date:  2021-06-30       Impact factor: 49.962

10.  Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years - United States, January-March 2021.

Authors:  Mark W Tenforde; Samantha M Olson; Wesley H Self; H Keipp Talbot; Christopher J Lindsell; Jay S Steingrub; Nathan I Shapiro; Adit A Ginde; David J Douin; Matthew E Prekker; Samuel M Brown; Ithan D Peltan; Michelle N Gong; Amira Mohamed; Akram Khan; Matthew C Exline; D Clark Files; Kevin W Gibbs; William B Stubblefield; Jonathan D Casey; Todd W Rice; Carlos G Grijalva; David N Hager; Arber Shehu; Nida Qadir; Steven Y Chang; Jennifer G Wilson; Manjusha Gaglani; Kempapura Murthy; Nicole Calhoun; Arnold S Monto; Emily T Martin; Anurag Malani; Richard K Zimmerman; Fernanda P Silveira; Donald B Middleton; Yuwei Zhu; Dayna Wyatt; Meagan Stephenson; Adrienne Baughman; Kelsey N Womack; Kimberly W Hart; Miwako Kobayashi; Jennifer R Verani; Manish M Patel
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2021-05-07       Impact factor: 35.301

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