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Literature DB >> 3500869

Immunological changes in beta-thalassemia major patients positive for HTLV-III antibodies.

M A Romeo¹, G Russo Mancuso, L Mauro, A Sciotto, M A Romeo¹, F Di Gregorio, G Giammanco, G Schiliro.

Abstract

Antibodies to HTLV-III were found in 6 of 206 Sicilian patients with thalassemia major, aged 1 to 30 years. None of the patients showed clinical signs related to immuno-deficiency syndromes. Immunological investigations carried out in all positive patients showed alterations similar to those found in thalassemic patients without antibodies to HTLV-III. These immunological changes could not depend on the HTLV-III infection, but could be related to the thalassemic condition.

Entities: Disease Species

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Year: 1987 PMID： 3500869 DOI： 10.1007/BF00145663

Source DB: PubMed Journal: Eur J Epidemiol ISSN： 0393-2990 Impact factor: 8.082

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References

12 in total

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Authors: M De Martino; M E Rossi; A T Muccioli; C Vullo; A Vierucci
Journal: Vox Sang Date: 1985 Impact factor: 2.144

Immunological changes in beta-thalassemia major patients positive for HTLV-III antibodies.

1. Lymphadenopathy syndrome in two thalassemic patients after LAV contamination by blood transfusion.

2. Antibodies to HTLV-III and the lymphadenopathy syndrome in multitransfused beta-thalassemia patients.

3. Lymphocyte changes in beta-thalassaemia major.

4. Altered T cell subsets and function in polytransfused beta-thalassemia patients: correlation with sex and age at first transfusion.

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