Literature DB >> 35008042

Pediatric Leprosy Profile in the Postelimination Era: A Study from Surabaya, Indonesia.

Novianti Rizky Reza1,2,3, Bagus Hario Kusumaputro1,2, Medhi Denisa Alinda1,2, Muhammad Yulianto Listiawan1,2, Hok Bing Thio3, Cita Rosita Sigit Prakoeswa1,2.   

Abstract

Children who live in leprosy-endemic areas are susceptible to infection due to early and frequent exposure to Mycobacterium leprae. Indonesia is on the verge of eliminating this disease (prevalence rate < 1/10,000 population), but pediatric leprosy continues to occur in low-endemic areas. This study aimed to evaluate pediatric leprosy over a decade in a tertiary hospital in Surabaya, Indonesia. A retrospective study of leprosy in children under 15 years old between 2010 and 2019 was conducted in the Morbus Hansen Division, Outpatient Clinic at Dr. Soetomo Hospital in Surabaya, Indonesia. Seventy pediatric leprosy cases were identified between 2010 and 2019, consisting of 58 multibacillary (MB)-type cases and 12 paucibacillary (PB)-type cases. Slit skin smear (SSS) was positive in 26 cases. There were two cases of grade-2 disability and 15 cases of leprosy reaction (erythema nodosum leprosum) in children at the time of diagnosis. There was an insignificant decline in the number of pediatric leprosy cases in the last 10 years. Cases and disabilities in children were found in some leprosy pocket areas even though the national elimination rate has been achieved. MB infections, disability, and treatment defaults were common problems in pediatric leprosy.

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Year:  2022        PMID: 35008042      PMCID: PMC8922520          DOI: 10.4269/ajtmh.21-0458

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   3.707


  12 in total

Review 1.  Slit-skin smear in leprosy: lest we forget it!

Authors:  V K Mahajan
Journal:  Indian J Lepr       Date:  2013 Oct-Dec

2.  Childhood leprosy in a tertiary-care hospital in Delhi, India: a reappraisal in the post-elimination era.

Authors:  Archana Singal; Sidharth Sonthalia; Deepika Pandhi
Journal:  Lepr Rev       Date:  2011-09       Impact factor: 0.537

3.  Childhood leprosy through the post-leprosy-elimination era: a retrospective analysis of epidemiological and clinical characteristics of disease over eleven years from a tertiary care hospital in North India.

Authors:  Sunil Dogra; Tarun Narang; Geeti Khullar; Ramesh Kumar; Uma Nahar Saikia
Journal:  Lepr Rev       Date:  2014-12       Impact factor: 0.537

4.  Leprosy profiles in post-elimination stage: a tertiary care hospital experience.

Authors:  Mohammad Rafiqul Mowla; Shamim Ara; Sanai Tripura
Journal:  Int J Dermatol       Date:  2015-07-30       Impact factor: 2.736

Review 5.  Leprosy: Clinical aspects and diagnostic techniques.

Authors:  Mayra B C Maymone; Melissa Laughter; Samantha Venkatesh; Mara M Dacso; P Narasimha Rao; Barbara M Stryjewska; Jeremy Hugh; Robert P Dellavalle; Cory A Dunnick
Journal:  J Am Acad Dermatol       Date:  2020-03-27       Impact factor: 11.527

Review 6.  Leprosy and women.

Authors:  Rashmi Sarkar; Swetalina Pradhan
Journal:  Int J Womens Dermatol       Date:  2016-10-25

7.  BCG Vaccination Status, Age, and Gender as Risk Factors for Leprosy in Endemic Areas in the Brazilian Amazon.

Authors:  Luana Nepomuceno Gondim Costa Lima; Jasna Letícia Pinto Paz; Maria do Perpétuo Socorro Corrêa Amador Silvestre; Letícia Siqueira Moura; Ismari Perini Furlaneto; Karla Valéria Batista Lima
Journal:  Infect Dis Rep       Date:  2020-11-27

8.  Widespread nasal carriage of Mycobacterium lepraeamong a healthy population in a hyperendemic region of northeastern Brazil.

Authors:  Luana Nepomuceno Gondim Costa Lima; Cristiane Cunha Frota; Rosa Maria Salani Mota; Rosa Livia Freitas Almeida; Maria Araci de Andrade Pontes; Heitor de Sá Gonçalves; Laura Cunha Rodrigues; Carl Kendall; Ligia Kerr
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-11       Impact factor: 2.743

Review 9.  Leprosy among children under 15 years of age: literature review.

Authors:  Marcela Bahia Barretto de Oliveira; Lucia Martins Diniz
Journal:  An Bras Dermatol       Date:  2016-04       Impact factor: 1.896

10.  Leprosy among schoolchildren in the Amazon region: A cross-sectional study of active search and possible source of infection by contact tracing.

Authors:  Valderiza Lourenço Pedrosa; Luiz Claudio Dias; Enrique Galban; André Leturiondo; Jamile Palheta; Monica Santos; Milton Ozório Moraes; Carolina Talhari
Journal:  PLoS Negl Trop Dis       Date:  2018-02-26
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  1 in total

Review 1.  Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management.

Authors:  Kou-Huang Chen; Cheng-Yao Lin; Shih-Bin Su; Kow-Tong Chen
Journal:  J Trop Med       Date:  2022-07-04
  1 in total

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