Literature DB >> 35005064

MPTP Parkinsonism and Implications for Understanding Parkinson's Disease.

Sohaila AlShimemeri1,2,3,4, Daniel G Di Luca1,2,3, Susan H Fox1,2,3.   

Abstract

Entities:  

Keywords:  MPTP; model; parkinsonism

Year:  2021        PMID： 35005064      PMCID： PMC8721821          DOI： 10.1002/mdc3.13344

Source DB:  PubMed          Journal:  Mov Disord Clin Pract        ISSN： 2330-1619


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  50 in total

1.  Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model.

Authors:  D A Di Monte; A McCormack; G Petzinger; A M Janson; M Quik; W J Langston
Journal:  Mov Disord       Date:  2000-05       Impact factor: 10.338

Review 2.  Translation of nondopaminergic treatments for levodopa-induced dyskinesia from MPTP-lesioned nonhuman primates to phase IIa clinical studies: keys to success and roads to failure.

Authors:  Susan H Fox; Anthony E Lang; Jonathan M Brotchie
Journal:  Mov Disord       Date:  2006-10       Impact factor: 10.338

3.  Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure.

Authors:  J W Langston; L S Forno; J Tetrud; A G Reeves; J A Kaplan; D Karluk
Journal:  Ann Neurol       Date:  1999-10       Impact factor: 10.422

4.  Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.

Authors:  M S Sandy; D Di Monte; P Cohen; M T Smith
Journal:  Basic Life Sci       Date:  1988

5.  VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.

Authors:  Ming-Kai Chen; Hiroto Kuwabara; Yun Zhou; Robert J Adams; James R Brasić; Jennifer L McGlothan; Tatyana Verina; Neal C Burton; Mohab Alexander; Anil Kumar; Dean F Wong; Tomás R Guilarte
Journal:  J Neurochem       Date:  2007-11-05       Impact factor: 5.372

Review 6.  The MPTP-lesioned marmoset model of Parkinson's disease: proposed efficacy thresholds that may potentially predict successful clinical trial results.

Authors:  Francis Beaudry; Philippe Huot
Journal:  J Neural Transm (Vienna)       Date:  2020-08-29       Impact factor: 3.575

7.  The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man.

Authors:  R S Burns; S P Markey; J M Phillips; C C Chiueh
Journal:  Can J Neurol Sci       Date:  1984-02       Impact factor: 2.104

8.  A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Authors:  R S Burns; C C Chiueh; S P Markey; M H Ebert; D M Jacobowitz; I J Kopin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

9.  The USA lags behind other agricultural nations in banning harmful pesticides.

Authors:  Nathan Donley
Journal:  Environ Health       Date:  2019-06-07       Impact factor: 5.984

Review 10.  Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson's disease? A critical reappraisal.

Authors:  Nitya Subrahmanian; Matthew J LaVoie
Journal:  Brain Res       Date:  2021-03-19       Impact factor: 3.610
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