Literature DB >> 35003502

Successful Treatment for Alpha Gal Mammal Product Allergy Using Auricular Acupuncture: A Case Series.

Mateo Bernal1, Martin Huecker2, Jacob Shreffler2, Olivia Mittel3, Joseph Mittel4, Nader Soliman5.   

Abstract

Introduction: Alpha gal syndrome (AGS) is an acquired allergy to mammalian products correlates with a tick bite(s) that appears to cause immune sensitization to an oligosaccharide in meat. Most publications on AGS describe no management other than avoidance of the offending agent(s). The objective of this study is to describe 2 populations of subjects who underwent Soliman Auricular Allergy Treatment (SAAT) for significant AGS meat and/or dairy allergy.
Methods: We performed a retrospective review of subjects treated at 2 different medical clinics that apply the same method of auricular acupuncture (SAAT) to AGS patients.
Results: A total of 137 patients presented to the 2 sites included in this study. The majority of patients were mammal product eaters before AGS; however, at the time of treatment only 7.3% of individuals (n = 10) actively consumed mammal products. Most subjects were reactive to beef (n = 135) and dairy (n = 95). The most common organ system involved in prior allergic reactions associated with AGS were gastrointestinal (n = 82, 59.9%) and dermatologic (n = 61, 44.5%). For those individuals with available outcome data on SAAT effectiveness (n = 126), 121 (96%) patients indicated that their symptoms were in remission after SAAT. Five individuals indicated that their symptoms were not in remission. Eleven individuals were unsure of treatment response or unable to be reached for follow-up.
Conclusion: The SAAT method showed effectiveness in the large majority of patients. No adverse reactions were noted as a result of auricular acupuncture. This alternative medicine approach to AGS management should be further studied in prospective trials with laboratory confirmation both before and after the procedure. This low-risk treatment shows promise in treating a medical condition that causes distress in an increasing number of patients. Copyright 2021, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  SAAT; Soliman Auricular Allergy Treatment; alpha gal allergy

Year:  2021        PMID: 35003502      PMCID: PMC8729907          DOI: 10.1089/acu.2021.0010

Source DB:  PubMed          Journal:  Med Acupunct        ISSN: 1933-6586


  20 in total

1.  Red meat desensitization in a child with delayed anaphylaxis due to alpha-Gal allergy.

Authors:  Esra Yucel; Sevgi Sipahi Cimen; Selin Varol; Ayse Suleyman; Cevdet Ozdemir; Zeynep Ulker Tamay
Journal:  Pediatr Allergy Immunol       Date:  2019-07-09       Impact factor: 6.377

2.  Predictive values of alpha-gal IgE levels and alpha-gal IgE: Total IgE ratio and oral food challenge-proven meat allergy in a population with a high prevalence of reported red meat allergy.

Authors:  Tshegofatso Mabelane; Wisdom Basera; Maresa Botha; Heidi Facey Thomas; Jordache Ramjith; Michael E Levin
Journal:  Pediatr Allergy Immunol       Date:  2018-09-28       Impact factor: 6.377

Review 3.  Diagnosis and Management of Patients with the α-Gal Syndrome.

Authors:  Thomas A E Platts-Mills; Rung-Chi Li; Behnam Keshavarz; Anna R Smith; Jeffrey M Wilson
Journal:  J Allergy Clin Immunol Pract       Date:  2019-09-28

Review 4.  Tick exposures and alpha-gal syndrome: A systematic review of the evidence.

Authors:  Ian Young; Chatura Prematunge; Kusala Pussegoda; Tricia Corrin; Lisa Waddell
Journal:  Ticks Tick Borne Dis       Date:  2021-01-27       Impact factor: 3.744

5.  Bracing for the Worst - Range Expansion of the Lone Star Tick in the Northeastern United States.

Authors:  Goudarz Molaei; Eliza A H Little; Scott C Williams; Kirby C Stafford
Journal:  N Engl J Med       Date:  2019-12-05       Impact factor: 91.245

Review 6.  Alpha-Gal-containing biologics and anaphylaxis.

Authors:  Yuko Chinuki; Eishin Morita
Journal:  Allergol Int       Date:  2019-04-30       Impact factor: 5.836

7.  An experimental evaluation of auricular diagnosis: the somatotopic mapping or musculoskeletal pain at ear acupuncture points.

Authors:  Terrence D Oleson; Richard J Kroening; David E Bresler
Journal:  Pain       Date:  1980-04       Impact factor: 6.961

8.  Clinical and Serological Characterization of the α-Gal Syndrome-Importance of Atopy for Symptom Severity in a European Cohort.

Authors:  M B Gea Kiewiet; Danijela Apostolovic; Maria Starkhammar; Jeanette Grundström; Carl Hamsten; Marianne van Hage
Journal:  J Allergy Clin Immunol Pract       Date:  2020-03-03

9.  Galactose-α-1,3-galactose (alpha-gal) allergy: first pediatric case in a series of patients in Spain.

Authors:  J Martín-Lázaro; R Núñez-Orjales; L A González-Guzmán; M T González; M Boquete; F Carballada
Journal:  Allergol Immunopathol (Madr)       Date:  2019-11-11       Impact factor: 1.667

10.  Discovery of Alpha-Gal-Containing Antigens in North American Tick Species Believed to Induce Red Meat Allergy.

Authors:  Gary Crispell; Scott P Commins; Stephanie A Archer-Hartman; Shailesh Choudhary; Guha Dharmarajan; Parastoo Azadi; Shahid Karim
Journal:  Front Immunol       Date:  2019-05-17       Impact factor: 7.561

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  1 in total

Review 1.  The Meat of the Matter: Understanding and Managing Alpha-Gal Syndrome.

Authors:  Jessica D Macdougall; Kevin O Thomas; Onyinye I Iweala
Journal:  Immunotargets Ther       Date:  2022-09-15
  1 in total

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