Literature DB >> 35002555

Strategies for Implementing Pediatric Dose Standardization: Considerations From the Vizient University Health System Consortium Pharmacy Network Pediatric Pharmacy Committee.

Christopher T Campbell1, Kristin H Wheatley2, Leanne Svoboda3, Courtney E Campbell1, Kelley R Norris1.   

Abstract

Pediatric patients are at a heightened risk for medication errors due to variability in medication ordering and administration. Dose rounding and standardization have been 2 practices historically used to reduce variability and improve medication safety. This article will describe strategies for implementing pediatric dose standardization. Local practice often dictates the operational decisions made at an institutional level, leading to a lack of a standard methodology. Vizient survey results demonstrate there is wide variation in dose standardization and ready-to-use (RTU) practices although most responding institutions have attempted to limit bedside manipulation to reduce medication error. There are many barriers to consider before pursuing dose standardization at an institution. These include selecting medications to standardize, calculating appropriate standardized doses, preparing RTU products, and supplying the products to the patient. Strategies to overcome implementation issues are described as well as identification of knowledge gaps related to the preparation and use of RTU products in the pediatric population. There is opportunity to enhance an institution's ability to provide RTU medications. Although there are several barriers, those that have had successful implementation have leveraged their information technology systems, garnered multidisciplinary support, and customized their practice to meet their operational demands. Copyright. Pediatric Pharmacy Association. All rights reserved. For permissions, email: mhelms@pediatricpharmacy.org 2022.

Entities:  

Keywords:  dose standardization; medication safety; pediatric; ready-to-use

Year:  2021        PMID: 35002555      PMCID: PMC8717617          DOI: 10.5863/1551-6776-27.1.19

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  10 in total

Review 1.  Automated dose-rounding recommendations for pediatric medications.

Authors:  Kevin B Johnson; Carlton K K Lee; S Andrew Spooner; Coda L Davison; Jill S Helmke; Stuart T Weinberg
Journal:  Pediatrics       Date:  2011-07-25       Impact factor: 7.124

2.  Observational study of accuracy in compounding i.v. admixtures at five hospitals.

Authors:  E A Flynn; R E Pearson; K N Barker
Journal:  Am J Health Syst Pharm       Date:  1997-04-15       Impact factor: 2.637

3.  Medication errors and adverse drug events in pediatric inpatients.

Authors:  R Kaushal; D W Bates; C Landrigan; K J McKenna; M D Clapp; F Federico; D A Goldmann
Journal:  JAMA       Date:  2001-04-25       Impact factor: 56.272

4.  Improving Pediatric Outcomes through Intravenous and Oral Medication Standardization.

Authors:  Mark W Mackay; Jared Cash; Fred Farr; Marc Holley; Kevin Jones; Sabrina Boehme
Journal:  J Pediatr Pharmacol Ther       Date:  2009-10

Review 5.  Electronic prescribing in pediatrics: toward safer and more effective medication management.

Authors:  Kevin B Johnson; Christoph U Lehmann
Journal:  Pediatrics       Date:  2013-03-25       Impact factor: 7.124

6.  Standard dose development for medications commonly used in the neonatal intensive care unit.

Authors:  Christine A Robinson; Anita Siu; Rachel Meyers; Ben H Lee; Jared Cash
Journal:  J Pediatr Pharmacol Ther       Date:  2014-04

7.  Standardization of dosage strengths in a pediatric unit dose drug distribution system.

Authors:  R C Bauman; A J Keenum
Journal:  Am J Hosp Pharm       Date:  1986-07

8.  The impact of a pediatric antibiotic standard dosing table on dosing errors.

Authors:  Mohammed A Aseeri
Journal:  J Pediatr Pharmacol Ther       Date:  2013-07

9.  Transition to a new electronic health record and pediatric medication safety: lessons learned in pediatrics within a large academic health system.

Authors:  Kimberly Whalen; Emily Lynch; Iman Moawad; Tanya John; Denise Lozowski; Brian M Cummings
Journal:  J Am Med Inform Assoc       Date:  2018-07-01       Impact factor: 4.497

Review 10.  The effect of computerized physician order entry on medication prescription errors and clinical outcome in pediatric and intensive care: a systematic review.

Authors:  Floor van Rosse; Barbara Maat; Carin M A Rademaker; Adrianus J van Vught; Antoine C G Egberts; Casper W Bollen
Journal:  Pediatrics       Date:  2009-04       Impact factor: 7.124

  10 in total

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