Literature DB >> 35001655

Circulating Cell-Free Mitochondrial DNA in Pregnancy.

Jessica L Bradshaw1, Spencer C Cushen1,2, Nicole R Phillips3, Styliani Goulopoulou1,4.   

Abstract

Circulating cell-free mitochondrial DNA (ccf-mtDNA) released upon cell injury or death stimulates diverse pattern recognition receptors to activate innate immune responses and initiate systemic inflammation. In this review, we discuss the temporal changes of ccf-mtDNA during pregnancy and its potential contribution to adverse pregnancy outcomes in pregnancy complications.

Entities:  

Keywords:  circulating DNA; gestation; maternal; mitochondria; preeclampsia

Mesh：

Substances：

Year:  2022        PMID： 35001655      PMCID： PMC9191172          DOI： 10.1152/physiol.00037.2021

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  104 in total

1.  Exposure to stimulatory CpG oligonucleotides during gestation induces maternal hypertension and excess vasoconstriction in pregnant rats.

Authors:  Styliani Goulopoulou; Camilla F Wenceslau; Cameron G McCarthy; Takayuki Matsumoto; R Clinton Webb
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-02-12       Impact factor: 4.733

Review 2.  Forms of extracellular mitochondria and their impact in health.

Authors:  Sophia Miliotis; Bryan Nicolalde; Mayra Ortega; Jackie Yepez; Andrés Caicedo
Journal:  Mitochondrion       Date:  2019-02-14       Impact factor: 4.160

3.  Insulin resistance and preeclampsia in gestational diabetes mellitus.

Authors:  Martin N Montoro; Siri L Kjos; Mary Chandler; Ruth K Peters; Anny H Xiang; Thomas A Buchanan
Journal:  Diabetes Care       Date:  2005-08       Impact factor: 19.112

Review 4.  The mitochondrial proteome and human disease.

Authors:  Sarah E Calvo; Vamsi K Mootha
Journal:  Annu Rev Genomics Hum Genet       Date:  2010       Impact factor: 8.929

5.  Toll-like receptor 9 activation: a novel mechanism linking placenta-derived mitochondrial DNA and vascular dysfunction in pre-eclampsia.

Authors:  Styliani Goulopoulou; Takayuki Matsumoto; Gisele F Bomfim; R Clinton Webb
Journal:  Clin Sci (Lond)       Date:  2012-10       Impact factor: 6.124

6.  Investigating mitochondrial dysfunction in gestational diabetes mellitus and elucidating if BMI is a causative mediator.

Authors:  Colm McElwain; Cathal M McCarthy
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2020-05-21       Impact factor: 2.435

7.  Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation.

Authors:  Jaswinder Sharma; Michael V Johnston; Mir Ahamed Hossain
Journal:  BMC Neurosci       Date:  2014-01-10       Impact factor: 3.288

8.  Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors.

Authors:  Shi-Bin Cheng; Akitoshi Nakashima; Warren J Huber; Sarah Davis; Sayani Banerjee; Zheping Huang; Shigeru Saito; Yoel Sadovsky; Surendra Sharma
Journal:  Cell Death Dis       Date:  2019-12-05       Impact factor: 8.469

9.  Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs.

Authors:  Kiran Todkar; Lilia Chikhi; Véronique Desjardins; Firas El-Mortada; Geneviève Pépin; Marc Germain
Journal:  Nat Commun       Date:  2021-03-30       Impact factor: 14.919

Review 10.  The Uprising of Mitochondrial DNA Biomarker in Cancer.

Authors:  Siti Zulaikha Nashwa Mohd Khair; Siti Muslihah Abd Radzak; Abdul Aziz Mohamed Yusoff
Journal:  Dis Markers       Date:  2021-07-15       Impact factor: 3.434
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