Literature DB >> 34999939

Caustic ingestion in children treated at a tertiary centre in South Africa: can upper endoscopy be omitted in asymptomatic patients?

Amanda Ngobese1,2, Saveshree Govender3,4, Nasheeta Peer5, Mahomed Hoosen Sheik-Gafoor3,4.   

Abstract

PURPOSE: Considering that clinical presentation and gastrointestinal tract (GIT) injuries post-caustic ingestion vary in children, this study aims to establish whether a correlation exists between clinical presentation and endoscopic findings.
METHODS: This retrospective study comprised patients referred to a paediatric surgical unit between 2016 and 2018 within 72 h post-caustic ingestion. Data collected included caustic agents ingested, clinical presentation, endoscopic findings and management. Oesophageal injuries were graded according to the Zargar's endoscopic classification and gastric injuries classified as mild to severe.
RESULTS: Fifty patients with a mean age of 2.4 years were managed during the study period. Potassium permanganate (KMNO4) was the most frequently ingested substance in 27 (54%) patients. All 30 (60%) asymptomatic patients had no positive endoscopic findings regardless of clinical signs. Among the symptomatic patients (n = 20), 15 (75%) had oesophageal injuries (p = 0.01). Stridor was associated with a higher grade of oesophageal injury (p = 0.007).
CONCLUSIONS: Clinical signs and symptoms post-caustic ingestion correlated with endoscopic findings in our study. Endoscopy can be safely omitted in asymptomatic patients, including those with isolated staining secondary to KMNO4 ingestion. Symptomatic patients should have an endoscopy performed within 48-72 h of the insult to diagnose injuries.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Caustic ingestion; Endoscopy; Oesophageal injury; Paediatric; Potassium permanganate; South Africa

Mesh:

Substances:

Year:  2022        PMID: 34999939     DOI: 10.1007/s00383-021-05045-3

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  17 in total

Review 1.  Caustic injury of the upper gastrointestinal tract: a comprehensive review.

Authors:  Sandro Contini; Carmelo Scarpignato
Journal:  World J Gastroenterol       Date:  2013-07-07       Impact factor: 5.742

2.  Update on the diagnosis and treatment of caustic ingestion.

Authors:  Michael Lupa; Jacqueline Magne; J Lindhe Guarisco; Ronald Amedee
Journal:  Ochsner J       Date:  2009

Review 3.  Caustic ingestion in children-A review.

Authors:  Marion Arnold; Alp Numanoglu
Journal:  Semin Pediatr Surg       Date:  2017-02-03       Impact factor: 2.754

4.  Pathophysiology and management of acute corrosive burns of the esophagus: results of treatment in 285 children.

Authors:  J A Haller; H G Andrews; J J White; M A Tamer; W W Cleveland
Journal:  J Pediatr Surg       Date:  1971-10       Impact factor: 2.545

5.  Is esophagogastroduodenoscopy necessary in all caustic ingestions?

Authors:  S K Gupta; J M Croffie; J F Fitzgerald
Journal:  J Pediatr Gastroenterol Nutr       Date:  2001-01       Impact factor: 2.839

6.  Caustic ingestion in children: is endoscopy always indicated? The results of an Italian multicenter observational study.

Authors:  Pietro Betalli; Diego Falchetti; Stefano Giuliani; Alessandro Pane; Luigi Dall'Oglio; Gian Luigi de Angelis; Mariano Caldore; Claudio Romano; Piergiorgio Gamba; Vincenzo Baldo
Journal:  Gastrointest Endosc       Date:  2008-04-29       Impact factor: 9.427

7.  Prediction of complications following unintentional caustic ingestion in children. Is endoscopy always necessary?

Authors:  H B Christesen
Journal:  Acta Paediatr       Date:  1995-10       Impact factor: 2.299

8.  Caustic ingestion management: world society of emergency surgery preliminary survey of expert opinion.

Authors:  Yoram Kluger; Ofir Ben Ishay; Massimo Sartelli; Amit Katz; Luca Ansaloni; Carlos Augusto Gomez; Walter Biffl; Fausto Catena; Gustavo P Fraga; Salomone Di Saverio; Augustin Goran; Wagih Ghnnam; Jeffry Kashuk; Ari Leppäniemi; Sanjay Marwah; Ernest E Moore; Miklosh Bala; Damien Massalou; Chirica Mircea; Luigi Bonavina
Journal:  World J Emerg Surg       Date:  2015-10-16       Impact factor: 5.469

9.  Caustic ingestion in adults: the role of endoscopic classification in predicting outcome.

Authors:  Hao-Tsai Cheng; Chi-Liang Cheng; Cheng-Hui Lin; Jui-Hsiang Tang; Yin-Yi Chu; Nai-Jen Liu; Pang-Chi Chen
Journal:  BMC Gastroenterol       Date:  2008-07-25       Impact factor: 3.067

Review 10.  Foreign Body and Caustic Substance Ingestion in Childhood.

Authors:  Mustafa Erman Dorterler; Tansel Günendi
Journal:  Open Access Emerg Med       Date:  2020-11-04
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