Literature DB >> 34999800

Preoperative radio-guided localization of lung nodules with I-125 seeds: experience with 32 patients at a single institution.

Sara Fra-Fernández1, Luis Gorospe-Sarasúa2, Odile Ajuria-Illarramendi3, Percy Enrique Serrano-Carvajal1, Gemma María Muñoz-Molina1, Alberto Cabañero-Sánchez1, Maria Eugenia Rioja-Martin3, Nicolás Moreno-Mata1.   

Abstract

OBJECTIVES: Videothoracoscopic visualization and/or palpation of pulmonary nodules may be difficult due to their location, small size or limited solid component. The purpose of this study is to present our experience with computed tomography (CT)-guided preoperative localization of pulmonary nodules by percutaneous marking with radio-labelled iodine-125 seeds.
METHODS: A total of 34 pulmonary nodules were marked under CT with the placement of 33 radio-labelled iodine-125 seeds in 32 consecutive patients.
RESULTS: All patients underwent biportal video-assisted thoracic surgery (VATS) and in no case was conversion to thoracotomy necessary. A total of 88.2% of the lung nodules were successfully resected. In the remaining 11.8%, migration of the seed to the pleural cavity occurred, although these nodules were still resected during VATS. Of all the patients with pneumothorax after the marking procedure, only one required chest tube placement (3.1%). No major postoperative complications were observed.
CONCLUSIONS: Preoperative marking of pulmonary nodules with I-125 seeds under CT guidance is a feasible and safe technique that allows their intraoperative identification and resection.
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Entities:  

Keywords:  Computed tomography; I-125 seeds; Preoperative localization; Pulmonary nodules; Radio-guided; Subsolid nodules; Video-assisted thoracic surgery

Mesh:

Substances:

Year:  2021        PMID: 34999800      PMCID: PMC8923417          DOI: 10.1093/icvts/ivab223

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN: 1569-9285


  29 in total

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Journal:  J Thorac Cardiovasc Surg       Date:  2006-08       Impact factor: 5.209

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Journal:  J Thorac Cardiovasc Surg       Date:  2014-09-16       Impact factor: 5.209

6.  A pilot study of the role of TC-99 radionuclide in localization of pulmonary nodular lesions for thoracoscopic resection.

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7.  Efficacy and complications of computed tomography-guided hook wire localization.

Authors:  Junji Ichinose; Tadasu Kohno; Sakashi Fujimori; Takashi Harano; Souichiro Suzuki
Journal:  Ann Thorac Surg       Date:  2013-07-26       Impact factor: 4.330

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Authors:  F X Lenglinger; C D Schwarz; W Artmann
Journal:  AJR Am J Roentgenol       Date:  1994-08       Impact factor: 3.959

9.  Lung cancer screening and video-assisted thoracic surgery.

Authors:  René Horsleben Petersen; Henrik Jessen Hansen; Asger Dirksen; Jesper Holst Pedersen
Journal:  J Thorac Oncol       Date:  2012-06       Impact factor: 15.609

10.  Near-infrared dye marking for thoracoscopic resection of small-sized pulmonary nodules: comparison of percutaneous and bronchoscopic injection techniques.

Authors:  Takashi Anayama; Kentaro Hirohashi; Ryohei Miyazaki; Hironobu Okada; Nobutaka Kawamoto; Marino Yamamoto; Takayuki Sato; Kazumasa Orihashi
Journal:  J Cardiothorac Surg       Date:  2018-01-12       Impact factor: 1.637

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