| Literature DB >> 3499953 |
T E Feasby1, J J Gilbert, A F Hahn, M Neilson.
Abstract
Lewis rats immunized with myelin and complete Freund's adjuvant were treated with cobra venom factor (CVF) which depletes the C3 component of complement. CVF given at day 9 delayed the onset of experimental allergic neuritis (EAN) by 2-3 days and when given at days 9 and 12 delayed the onset of EAN by 4-5 days. Lumbar nerve roots of CVF-treated rats had significantly less demyelination than those from control EAN rats.Entities:
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Year: 1987 PMID: 3499953 DOI: 10.1016/0006-8993(87)90572-5
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252