Literature DB >> 34997468

Predictive Factors for Developing GERD After Sleeve Gastrectomy: Is Preoperative Endoscopy Necessary?

Omar Bellorin1, James C Senturk2,3, Mariana Vigiola Cruz1, Gregory Dakin1, Cheguevara Afaneh1.   

Abstract

INTRODUCTION: Sleeve gastrectomy (SG) is the most common bariatric procedure performed in the USA. There is a concern for new gastroesophageal reflux disease (GERD) and Barrett's esophagus after SG. Endoscopic screening before bariatric surgery is controversial. We sought to identify preoperative endoscopic factors that may predict the development of GERD after SG.
METHODS: We prospectively evaluated 217 patients undergoing primary robotic-assisted SG. All patients underwent endoscopy before SG and for-cause postoperatively. Patients were followed for the development of GERD, diagnosed by either biopsy-proven reflux esophagitis or a positive esophageal pH test. Patients were separated into 2 groups: Those who developed GERD after surgery (GERD group) and those who did not (No GERD group). Patients with a positive preoperative pH test, LA Grade B or greater esophagitis, or hiatal hernia > 5 cm on preoperative endoscopy were counseled to undergo gastric bypass and excluded.
RESULTS: There were more males in the No GERD group (25.6% vs. 8.1%; p = 0.02). More patients had preoperative heartburn symptoms in the GERD group (40.5% vs. 23.9%; p = 0.04). Endoscopically identified esophagitis was more common in the GERD group (29.7% vs. 13.3%; p = 0.01), as was biopsy-proven esophagitis (24.3% vs. 11.1%; p = 0.03). There was no significant difference in the incidence or size of hiatal hernia or in the rate of H. pylori infection between the groups. On multivariate analysis, the strongest predictors of GERD after SG were endoscopically identified esophagitis (odds ratio [OR] 2.79; 95% confidence interval [CI]1.17-6.69; p = 0.02) and biopsy-proven esophagitis (OR 2.80; 95% CI 1.06-7.37; p = 0.04). Male patients were less likely to develop GERD after SG (OR 0.23; 95% CI 0.06-0.85; p = 0.03).
CONCLUSION: Our findings strengthen the rationale for routine preoperative endoscopy and highlight critical clinical and endoscopic criteria that should prompt consideration of alternatives to SG for weight loss.
© 2021. The Society for Surgery of the Alimentary Tract.

Entities:  

Keywords:  Bariatric endoscopy; Esophagitis; GERD; Reflux; Sleeve gastrectomy

Mesh:

Year:  2022        PMID: 34997468     DOI: 10.1007/s11605-021-05207-7

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  17 in total

1.  Gastroesophageal reflux disease and Barrett's esophagus after laparoscopic sleeve gastrectomy: a possible, underestimated long-term complication.

Authors:  Alfredo Genco; Emanuele Soricelli; Giovanni Casella; Roberta Maselli; Lidia Castagneto-Gissey; Nicola Di Lorenzo; Nicola Basso
Journal:  Surg Obes Relat Dis       Date:  2016-12-09       Impact factor: 4.734

2.  Improvement of gastroesophageal reflux symptoms after standardized laparoscopic sleeve gastrectomy.

Authors:  Jorge Daes; Manuel E Jimenez; Nadim Said; Rodolfo Dennis
Journal:  Obes Surg       Date:  2014-04       Impact factor: 4.129

3.  Reflux, Sleeve Dilation, and Barrett's Esophagus after Laparoscopic Sleeve Gastrectomy: Long-Term Follow-Up.

Authors:  Daniel Moritz Felsenreich; Ronald Kefurt; Martin Schermann; Philipp Beckerhinn; Ivan Kristo; Michael Krebs; Gerhard Prager; Felix B Langer
Journal:  Obes Surg       Date:  2017-12       Impact factor: 4.129

Review 4.  Sleeve gastrectomy and anti-reflux procedures.

Authors:  Christopher Crawford; Kyle Gibbens; Daniel Lomelin; Crystal Krause; Anton Simorov; Dmitry Oleynikov
Journal:  Surg Endosc       Date:  2016-07-20       Impact factor: 4.584

5.  Prevalence of Barrett's Esophagus in Bariatric Patients Undergoing Sleeve Gastrectomy.

Authors:  Italo Braghetto; Attila Csendes
Journal:  Obes Surg       Date:  2016-04       Impact factor: 4.129

6.  Routine Screening Endoscopy before Bariatric Surgery: Is It Necessary?

Authors:  Victoria Gómez; Rajat Bhalla; Michael G Heckman; Paul T Kröner Florit; Nancy N Diehl; Bhupendra Rawal; Scott A Lynch; David S Loeb
Journal:  Bariatr Surg Pract Patient Care       Date:  2014-12-01       Impact factor: 0.607

Review 7.  Preoperative Endoscopy Prior to Bariatric Surgery: a Systematic Review and Meta-Analysis of the Literature.

Authors:  Manish Parikh; Jennifer Liu; Dorice Vieira; Demetrios Tzimas; Daniel Horwitz; Andrew Antony; John K Saunders; Akuezunkpa Ude-Welcome; Adam Goodman
Journal:  Obes Surg       Date:  2016-12       Impact factor: 4.129

8.  BRAVO esophageal pH monitoring: more cost-effective than empiric medical therapy for suspected gastroesophageal reflux.

Authors:  Cheguevara Afaneh; Veronica Zoghbi; Brendan M Finnerty; Anna Aronova; David Kleiman; Thomas Ciecierega; Carl Crawford; Thomas J Fahey; Rasa Zarnegar
Journal:  Surg Endosc       Date:  2015-11-04       Impact factor: 4.584

9.  Does laparoscopic sleeve gastrectomy have any influence on gastroesophageal reflux disease? Preliminary results.

Authors:  Verónica Gorodner; Rudolf Buxhoeveden; Gastón Clemente; Laura Solé; Luis Caro; Alejandro Grigaites
Journal:  Surg Endosc       Date:  2014-10-11       Impact factor: 4.584

10.  Routine surveillance endoscopy before and after sleeve gastrectomy?

Authors:  Radwan Kassir; Rani Kassir; Bénédicte Deparseval; Sarah Bekkar; Chloé Serayssol; Olivier Favre; Pierre-Philippe Garnier
Journal:  World J Gastrointest Endosc       Date:  2019-01-16
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  2 in total

1.  Prevalence, Predictors, and Management of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy: a Multicenter Cohort Study.

Authors:  Ayman El Nakeeb; Hassan Aldossary; Ahmed Zaid; Mohamed El Sorogy; Mohamad Elrefai; Mohamed Attia; Alaa Mostafa Sewefy; Taha Kayed; Mubarak Al-Shari Aldawsari; Hathal Mashan Al Dossari; Mohammed M Mohammed
Journal:  Obes Surg       Date:  2022-09-10       Impact factor: 3.479

2.  Development and Validation of an Artificial Intelligence-Based Model to Predict Gastroesophageal Reflux Disease After Sleeve Gastrectomy.

Authors:  Sameh Hany Emile; Waleed Ghareeb; Hossam Elfeki; Mohamed El Sorogy; Amgad Fouad; Mohamed Elrefai
Journal:  Obes Surg       Date:  2022-05-21       Impact factor: 3.479

  2 in total

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