Literature DB >> 34995688

Mathematical modeling suggests that entry-inhibitor bulevirtide may interfere with hepatitis D virus clearance from circulation.

Louis Shekhtman1, Scott J Cotler2, Alexander Ploss3, Harel Dahari4.   

Abstract

Entities:  

Keywords:  HDV kinetics; bulevirtide; mathematical modeling

Mesh：

Substances：

Year:  2022        PMID： 34995688      PMCID： PMC9018506          DOI： 10.1016/j.jhep.2021.12.030

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   30.083


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  9 in total

Review 1.  Strategies to inhibit entry of HBV and HDV into hepatocytes.

Authors:  Stephan Urban; Ralf Bartenschlager; Ralf Kubitz; Fabien Zoulim
Journal:  Gastroenterology       Date:  2014-04-25       Impact factor: 22.682

2.  Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial.

Authors:  Christopher Koh; Laetitia Canini; Harel Dahari; Xiongce Zhao; Susan L Uprichard; Vanessa Haynes-Williams; Mark A Winters; Gitanjali Subramanya; Stewart L Cooper; Peter Pinto; Erin F Wolff; Rachel Bishop; Ma Ai Thanda Han; Scott J Cotler; David E Kleiner; Onur Keskin; Ramazan Idilman; Cihan Yurdaydin; Jeffrey S Glenn; Theo Heller
Journal:  Lancet Infect Dis       Date:  2015-07-16       Impact factor: 25.071

3.  Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.

Authors:  Katja Giersch; Oliver D Bhadra; Maura Dandri; Marc Lütgehetmann; Tassilo Volz; Lena Allweiss; Kristoffer Riecken; Boris Fehse; Ansgar W Lohse; Joerg Petersen; Camille Sureau; Stephan Urban
Journal:  Gut       Date:  2017-12-07       Impact factor: 23.059

4.  Understanding early serum hepatitis D virus and hepatitis B surface antigen kinetics during pegylated interferon-alpha therapy via mathematical modeling.

Authors:  Jeremie Guedj; Yaron Rotman; Scott J Cotler; Christopher Koh; Peter Schmid; Jeff Albrecht; Vanessa Haynes-Williams; T Jake Liang; Jay H Hoofnagle; Theo Heller; Harel Dahari
Journal:  Hepatology       Date:  2014-10-27       Impact factor: 17.425

Review 5.  The use of humanized mice for studies of viral pathogenesis and immunity.

Authors:  Florian Douam; Alexander Ploss
Journal:  Curr Opin Virol       Date:  2018-03-28       Impact factor: 7.090

6.  Safety and effectiveness of up to 3 years' bulevirtide monotherapy in patients with HDV-related cirrhosis.

Authors:  Alessandro Loglio; Peter Ferenci; Sara Colonia Uceda Renteria; Christine Y L Tham; Caroline Scholtes; Heidemarie Holzmann; Florian van Bömmel; Marta Borghi; Riccardo Perbellini; Alessandro Rimondi; Elisa Farina; Elena Trombetta; Maria Manunta; Laura Porretti; Daniele Prati; Ferruccio Ceriotti; Fabien Zoulim; Antonio Bertoletti; Pietro Lampertico
Journal:  J Hepatol       Date:  2021-10-23       Impact factor: 25.083

7.  Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance.

Authors:  Louis Shekhtman; Miquel Navasa; Natasha Sansone; Gonzalo Crespo; Gitanjali Subramanya; Tje Lin Chung; E Fabian Cardozo-Ojeda; Sofía Pérez-Del-Pulgar; Alan S Perelson; Scott J Cotler; Xavier Forns; Susan L Uprichard; Harel Dahari
Journal:  Elife       Date:  2021-11-03       Impact factor: 8.140

8.  Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg.

Authors:  Louis Shekhtman; Scott J Cotler; Leeor Hershkovich; Susan L Uprichard; Michel Bazinet; Victor Pantea; Valentin Cebotarescu; Lilia Cojuhari; Pavlina Jimbei; Adalbert Krawczyk; Ulf Dittmer; Andrew Vaillant; Harel Dahari
Journal:  Sci Rep       Date:  2020-05-12       Impact factor: 4.379

9.  Response guided therapy for reducing duration of direct acting antivirals in chronic hepatitis C infected patients: a Pilot study.

Authors:  Ohad Etzion; Harel Dahari; David Yardeni; Assaf Issachar; Anat Nevo-Shor; Michal Cohen-Naftaly; Yaffa Ashur; Susan L Uprichard; Orly Sneh Arbib; Daniela Munteanu; Marius Braun; Scott J Cotler; Naim Abufreha; Ayelet Keren-Naus; Yonat Shemer-Avni; Orna Mor; Jayanah Murad; Victor Novack; Amir Shlomai
Journal:  Sci Rep       Date:  2020-10-20       Impact factor: 4.379
  9 in total
  1 in total

1.  Advances in Parameter Estimation and Learning from Data for Mathematical Models of Hepatitis C Viral Kinetics.

Authors:  Vladimir Reinharz; Alexander Churkin; Harel Dahari; Danny Barash
Journal:  Mathematics (Basel)       Date:  2022-06-19
  1 in total

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