Literature DB >> 3499352

Inositol trisphosphate accumulation by high K+ stimulation in cultured adrenal chromaffin cells.

N Sasakawa1, T Nakaki, S Yamamoto, R Kato.   

Abstract

Stimulation with high K+ (KCl, 56 mM) of myo-[3H]inositol-prelabelled cells increased Ca2+ uptake and [3H]inositol trisphosphate (IP3) accumulation in a concentration-dependent manner. Nifedipine, a Ca2+ channel antagonist, inhibited high K+-induced [3H]IP3 accumulation and 45Ca2+ uptake with a similar potency. Furthermore, ionomycin (1 microM), a Ca2+ ionophore, also induced 45Ca2+ uptake and [3H]IP3 accumulation. These results indicate the existence of the Ca2+ uptake-triggered mechanism of IP3 formation in cultured adrenal chromaffin cells.

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Year:  1987        PMID： 3499352     DOI： 10.1016/0014-5793(87)80330-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

Review 1.  Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.

Authors:  S Cockcroft; G M Thomas
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

2.  Functional shift from muscarinic to nicotinic cholinergic receptors involved in inositol trisphosphate and cyclic GMP accumulation during the primary culture of adrenal chromaffin cells.

Authors:  T Nakaki; N Sasakawa; S Yamamoto; R Kato
Journal:  Biochem J       Date:  1988-04-15       Impact factor: 3.857

3.  Pertussis-toxin-sensitive inhibition by (-) baclofen of Ca signals in bovine chromaffin cells.

Authors:  P Doroshenko; E Neher
Journal:  Pflugers Arch       Date:  1991-11       Impact factor: 3.657

4.  Distinct targets for tetanus and botulinum A neurotoxins within the signal transducing pathway in chromaffin cells.

Authors:  P Marxen; F Bartels; G Ahnert-Hilger; H Bigalke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-10       Impact factor: 3.000

5.  Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.

Authors:  V Allen; P Swigart; R Cheung; S Cockcroft; M Katan
Journal:  Biochem J       Date:  1997-10-15       Impact factor: 3.857

6.  Regulation of the formation of inositol phosphates by calcium, guanine nucleotides and ATP in digitonin-permeabilized bovine adrenal chromaffin cells.

Authors:  D A Eberhard; R W Holz
Journal:  Biochem J       Date:  1991-10-15       Impact factor: 3.857

7.  Ca2+ influx induced by the Ca(2+)-ATPase inhibitors 2,5-di-(t-butyl)-1,4-benzohydroquinone and thapsigargin in bovine adrenal chromaffin cells.

Authors:  I M Robinson; T R Cheek; R D Burgoyne
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857

8.  Inhibition of prostaglandin E2-induced phosphoinositide metabolism by phorbol ester in bovine adrenal chromaffin cells.

Authors:  H Yokohama; M Negishi; K Sugama; H Hayashi; S Ito; O Hayaishi
Journal:  Biochem J       Date:  1988-11-01       Impact factor: 3.857
  8 in total

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