Literature DB >> 34988768

Contribution of cost to treatment nonadherence in the US breast cancer survivors: a population-based analysis.

Caiwei Zheng1, Anees B Chagpar2.   

Abstract

INTRODUCTION: Breast cancer survivors are often prescribed medications for at least 5 years to reduce recurrence risk, yet some forego this treatment due to cost. We sought to elucidate the prevalence of this and the factors contributing to it.
METHODS: The National Health Interview Survey (NHIS) is a population-based survey, representative of the civilian non-institutionalized US population, administered annually by the CDC. People diagnosed with breast cancer within the past 5 years surveyed in the 2018 NHIS formed the cohort of interest.
RESULTS: Of the 24,858 breast cancer survivors surveyed, representing 244,607,304 in the population, 6.32% stated that they needed a prescription medicine within the past 12 months, but didn't get it filled because they couldn't afford it. Of those who had gotten a prescription within the past 12 months, 5.71, 5.94 and 7.48% had either skipped doses, taken less medication than prescribed, or delayed filling a prescription, respectively, to save money. 11.99% of people had done at least one of these, thereby foregoing treatment. On bivariate analyses, factors associated with foregoing treatment included age, race, education, family income, and insurance status (p < 0.001 for all). On multivariable analysis, age, race, family income, and insurance status were all independent predictors of foregoing treatment (p < 0.001 for all); education status was not significant in the model (p = 0.211).
CONCLUSION: Roughly 12% of breast cancer survivors who are prescribed medications within the first 5 years of their diagnosis will forego treatment due to cost. Family income and insurance status are key modifiable drivers of this.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Barriers; Breast cancer; Cost; Endocrine therapy; Non-adherence

Mesh:

Year:  2022        PMID: 34988768     DOI: 10.1007/s10549-022-06510-w

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  1 in total

1.  Breast Cancer Survivorship: Where Are We Today?

Authors:  Patricia A Ganz; Pamela J Goodwin
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

  1 in total

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