Literature DB >> 34985756

Cell-Free Paper-Based Analysis of Gut Microbiota and Host Biomarkers.

Melissa K Takahashi1, Xiao Tan2,3,4,5, Aaron J Dy2,5,6.   

Abstract

The gut microbiome and its interactions with the host have been shown to affect several aspects of human health and disease. Investigations to elucidate these mechanisms typically involve sequence analysis of fecal samples. To support these studies, we present methods to design RNA toehold switch sensors to detect microbial and host transcripts. The sensors are embedded in paper-based, cell-free reactions that enable affordable and rapid analysis of microbiome samples.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Biosensors; Gut microbiota; Host biomarkers; NASBA; Paper-based diagnostics; RNA toehold switch

Mesh:

Substances:

Year:  2022        PMID: 34985756     DOI: 10.1007/978-1-0716-1998-8_22

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  16 in total

1.  Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components.

Authors:  Keith Pardee; Alexander A Green; Melissa K Takahashi; Dana Braff; Guillaume Lambert; Jeong Wook Lee; Tom Ferrante; Duo Ma; Nina Donghia; Melina Fan; Nichole M Daringer; Irene Bosch; Dawn M Dudley; David H O'Connor; Lee Gehrke; James J Collins
Journal:  Cell       Date:  2016-05-06       Impact factor: 41.582

Review 2.  An integrative view of microbiome-host interactions in inflammatory bowel diseases.

Authors:  Marta Wlodarska; Aleksandar D Kostic; Ramnik J Xavier
Journal:  Cell Host Microbe       Date:  2015-05-13       Impact factor: 21.023

3.  Intestinal inflammatory biomarkers and outcome in pediatric Clostridium difficile infections.

Authors:  Rana E El Feghaly; Jennifer L Stauber; Phillip I Tarr; David B Haslam
Journal:  J Pediatr       Date:  2013-09-04       Impact factor: 4.406

Review 4.  Inflammatory bowel disease as a model for translating the microbiome.

Authors:  Curtis Huttenhower; Aleksandar D Kostic; Ramnik J Xavier
Journal:  Immunity       Date:  2014-06-19       Impact factor: 31.745

5.  Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection.

Authors:  Rana E El Feghaly; Jennifer L Stauber; Elena Deych; Carlos Gonzalez; Phillip I Tarr; David B Haslam
Journal:  Clin Infect Dis       Date:  2013-03-13       Impact factor: 9.079

6.  Persistent gut microbiota immaturity in malnourished Bangladeshi children.

Authors:  Sathish Subramanian; Sayeeda Huq; Tanya Yatsunenko; Rashidul Haque; Mustafa Mahfuz; Mohammed A Alam; Amber Benezra; Joseph DeStefano; Martin F Meier; Brian D Muegge; Michael J Barratt; Laura G VanArendonk; Qunyuan Zhang; Michael A Province; William A Petri; Tahmeed Ahmed; Jeffrey I Gordon
Journal:  Nature       Date:  2014-06-04       Impact factor: 49.962

Review 7.  Functional Genomics of Host-Microbiome Interactions in Humans.

Authors:  Francesca Luca; Sonia S Kupfer; Dan Knights; Alexander Khoruts; Ran Blekhman
Journal:  Trends Genet       Date:  2017-10-26       Impact factor: 11.639

8.  Paper-based synthetic gene networks.

Authors:  Keith Pardee; Alexander A Green; Tom Ferrante; D Ewen Cameron; Ajay DaleyKeyser; Peng Yin; James J Collins
Journal:  Cell       Date:  2014-10-23       Impact factor: 41.582

9.  A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers.

Authors:  Melissa K Takahashi; Xiao Tan; Aaron J Dy; Dana Braff; Reid T Akana; Yoshikazu Furuta; Nina Donghia; Ashwin Ananthakrishnan; James J Collins
Journal:  Nat Commun       Date:  2018-08-21       Impact factor: 14.919

10.  Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.

Authors:  Robert A Koeth; Zeneng Wang; Bruce S Levison; Jennifer A Buffa; Elin Org; Brendan T Sheehy; Earl B Britt; Xiaoming Fu; Yuping Wu; Lin Li; Jonathan D Smith; Joseph A DiDonato; Jun Chen; Hongzhe Li; Gary D Wu; James D Lewis; Manya Warrier; J Mark Brown; Ronald M Krauss; W H Wilson Tang; Frederic D Bushman; Aldons J Lusis; Stanley L Hazen
Journal:  Nat Med       Date:  2013-04-07       Impact factor: 53.440

View more
  1 in total

Review 1.  Material Engineering in Gut Microbiome and Human Health.

Authors:  Letao Yang; Lin Y Hung; Yuefei Zhu; Suwan Ding; Kara G Margolis; Kam W Leong
Journal:  Research (Wash D C)       Date:  2022-07-20
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.