| Literature DB >> 34985566 |
Toni Hospach1, Gerd Horneff2, Denis Poddubnyy3.
Abstract
Axial spondylarthritis in adulthood (SpAA) is frequently initially manifested as a sacroiliitis, whereas this not true for enthesitis-related arthritis (EAA), which begins in childhood and adolescence. Classically, EAA begins with peripheral arthritis and only a part transitions into a juvenile SpA (jSpA) or SpAA. The criteria used for classification of SpAA and EAA are currently being validated and revised. For the first time imaging is included for EAA. For both diseases nonsteroidal anti-inflammatory drugs (NSAID) are initially used therapeutically, followed by biologicals or synthetic targeted disease-modifying drugs in refractory courses. Steroids should be avoided in long-term treatment. For optimal transition and further care in adulthood, a close cooperation between internistic and pediatric rheumatologists is necessary.Entities:
Keywords: Biologicals; Classification; Enthesitis-related arthritis; Imaging; Nonsteroidal anti-inflammatory agents; Spondyloarthritis
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Year: 2022 PMID: 34985566 DOI: 10.1007/s00393-021-01135-8
Source DB: PubMed Journal: Z Rheumatol ISSN: 0340-1855 Impact factor: 1.372