Literature DB >> 34984124

Atypical Presentation of Dysphagia in a Patient Diagnosed Later With Dermatomyositis: A Case Report.

Ali Elmdaah1, Abuobeida Ali1, Zulakha Nadeem1, Mohamed Habieb1, John Pradeep2, Kevin Metangi2.   

Abstract

Dysphagia has been reported in 10%-73% of patients with dermatomyositis. We present the case of a 58-year-old female patient who presented to the emergency department of Peterborough City Hospital with acute-onset difficulty in swallowing. Physical examination demonstrates proximal muscle weakness of the upper limbs and symmetrical skin rash over the face, chest, and thighs. Both clinical and laboratory findings pointed towards the diagnosis dermatomyositis. Oesophagogastroduodenoscopy identified no significant abnormality reducing the possibility of dysphagia due to an intrusive lesion, such as an abscess or a malignancy. MRI scan of the lower limbs revealed evidence of proximal myositis. CT neck, chest, abdomen and pelvis exclude any associated malignancy. The patient was treated initially with intravenous pulses of methylprednisolone for three days, and then switched to oral prednisolone and cyclophosphamide cycles and was considered for intravenous immunoglobulins as her symptoms had not completely resolved.
Copyright © 2021, Elmdaah et al.

Entities:  

Keywords:  dermatomyositis; diabetes mellitus; dysphagia; gottron's sign; myositis

Year:  2021        PMID: 34984124      PMCID: PMC8714034          DOI: 10.7759/cureus.19964

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  12 in total

1.  Incidence and predictive factors for malignancies in 136 Japanese patients with dermatomyositis, polymyositis and clinically amyopathic dermatomyositis.

Authors:  Kohei Azuma; Hidehiro Yamada; Michiko Ohkubo; Yoshioki Yamasaki; Masaomi Yamasaki; Machiko Mizushima; Shoichi Ozaki
Journal:  Mod Rheumatol       Date:  2010-10-05       Impact factor: 3.023

2.  Intravenous immunoglobulins for steroid-refractory esophageal involvement related to polymyositis and dermatomyositis: a series of 73 patients.

Authors:  I Marie; J-F Menard; P Y Hatron; E Hachulla; L Mouthon; K Tiev; P Ducrotte; P Cherin
Journal:  Arthritis Care Res (Hoboken)       Date:  2010-12       Impact factor: 4.794

3.  Life-threatening oropharyngeal aphagia as the major manifestation of dermatomyositis.

Authors:  Amir Dagan; Doron Markovits; Yolanda Braun-Moscovici; Alexander Rozin; Kohava Toledano; Alexandra Balbir-Gurman
Journal:  Isr Med Assoc J       Date:  2013-08       Impact factor: 0.892

4.  Recovery of barium swallow radiographic abnormalities in a patient with dermatomyositis and severe dysphagia after high-dose intravenous immunoglobulins.

Authors:  Florenzo Iannone; Margherita Giannini; Giovanni Lapadula
Journal:  J Clin Rheumatol       Date:  2015-06       Impact factor: 3.517

5.  Pharyngeal dysphagia in inflammatory muscle diseases resulting from impaired suprahyoid musculature.

Authors:  P Claire Langdon; Kylie Mulcahy; Kelly L Shepherd; Vincent H Low; Frank L Mastaglia
Journal:  Dysphagia       Date:  2011-12-30       Impact factor: 3.438

Review 6.  Treatment of inflammatory myopathies.

Authors:  A C Cordeiro; D A Isenberg
Journal:  Postgrad Med J       Date:  2006-07       Impact factor: 2.401

7.  Cancer-associated myositis: clinical features and prognostic signs.

Authors:  Andrea Ponyi; Tamás Constantin; Miklós Garami; Csilla András; Béla Tállai; Andrea Váncsa; Lajos Gergely; Katalin Dankó
Journal:  Ann N Y Acad Sci       Date:  2005-06       Impact factor: 5.691

Review 8.  Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis.

Authors:  E H S Choy; J E Hoogendijk; B Lecky; J B Winer
Journal:  Cochrane Database Syst Rev       Date:  2005-07-20

Review 9.  Review article: the gastrointestinal complications of myositis.

Authors:  E C Ebert
Journal:  Aliment Pharmacol Ther       Date:  2009-11-03       Impact factor: 8.171

10.  Dysphagia in inflammatory myopathy: clinical characteristics, treatment strategies, and outcome in 62 patients.

Authors:  Terry H Oh; Kathlyn A Brumfield; Tanya L Hoskin; Kathryn A Stolp; Joseph A Murray; Jeffrey R Bassford
Journal:  Mayo Clin Proc       Date:  2007-04       Impact factor: 7.616

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