| Literature DB >> 34980162 |
Hongying Chen1,2,3, Jiang Deng1,2,3, Xintong Yao4,5, Yungang He1,2,3, Hanyue Li1,2,3, Zhixiang Jian1,2,3, Yi Tang1,2,3, Xiaoqing Zhang1,2,3, Jingqing Zhang6, Hongwei Dai7,8,9.
Abstract
Entities:
Year: 2022 PMID: 34980162 PMCID: PMC8722323 DOI: 10.1186/s12951-021-01185-9
Source DB: PubMed Journal: J Nanobiotechnology ISSN: 1477-3155 Impact factor: 10.435
Fig. 8Preliminary biosafety assay of Asp8[H40-TPZ/IR780@(RBC-H)] NPs. a The body weight change curves of nude mice bearing WSU-HN6 tumor after various treatment (n = 5, mean ± SD). b–d Main blood biochemical parameters of liver function including ALP, ALT, and AST. e, f Main biochemical parameters of kidney function including BUN and CRE. g H&E staining slices of major organs including heart, liver, spleen, lung, and kidney from each group. The mice without any therapy were as a blank group (scale bar = 50 μm). (A: Normal saline, B: Normal saline + Laser, C: TPZ + Laser, D: Asp8[H40-PEG@(RBC-H)] + Laser, E: H40-PEG loading IR780 + Laser, F: H40-TPZ/IR780@(RBC-H) + Laser, and G: Asp8[H40-TPZ/IR780@(RBC-H)] + Laser). ***p < 0.001