Michael J Murphy1,2, Aileen A Dow1,2. 1. Dr. Murphy is with the Department of Dermatology, UConn Health in Farmington, Connecticut. 2. Ms. Dow is with si SKIN Organics® in Canton, Connecticut.
Abstract
BACKGROUND: There is a growing body of in-vitro and in-vivo laboratory research on the skin bioactive properties of macroalgae. OBJECTIVE: We sought to examine the scientific literature for evidence supporting the clinical safety and efficacy of macroalgae-derived ingredients in cosmeceuticals. METHODS: We performed a systematic review of scientific and medical electronic databases for published, peer-reviewed, randomized controlled trials and nonrandomized reports on the clinical bioactivity of topical macroalgae extracts in skin. RESULTS: Several human studies report scientific data supporting the safety and efficacy of macroalgae-based skincare products, focusing on skin-moisturizing, anti-melanogenic, and anti-cellulite (slimming) benefits. CONCLUSIONS: Further clinical research is necessary to determine the long-term safety, efficacy, optimal concentration and formulation of macroalgae extracts in cosmeceuticals with respect to previously reported and yet uninvestigated skin-directed potential functionally and bioactivity.
BACKGROUND: There is a growing body of in-vitro and in-vivo laboratory research on the skin bioactive properties of macroalgae. OBJECTIVE: We sought to examine the scientific literature for evidence supporting the clinical safety and efficacy of macroalgae-derived ingredients in cosmeceuticals. METHODS: We performed a systematic review of scientific and medical electronic databases for published, peer-reviewed, randomized controlled trials and nonrandomized reports on the clinical bioactivity of topical macroalgae extracts in skin. RESULTS: Several human studies report scientific data supporting the safety and efficacy of macroalgae-based skincare products, focusing on skin-moisturizing, anti-melanogenic, and anti-cellulite (slimming) benefits. CONCLUSIONS: Further clinical research is necessary to determine the long-term safety, efficacy, optimal concentration and formulation of macroalgae extracts in cosmeceuticals with respect to previously reported and yet uninvestigated skin-directed potential functionally and bioactivity.
Authors: Tamara Al-Bader; Adam Byrne; Johanna Gillbro; Andrea Mitarotonda; Adeline Metois; Francis Vial; Anthony V Rawlings; Aurelie Laloeuf Journal: J Cosmet Dermatol Date: 2012-03 Impact factor: 2.696
Authors: Hossam S El-Beltagi; Amal A Mohamed; Heba I Mohamed; Khaled M A Ramadan; Aminah A Barqawi; Abdallah Tageldein Mansour Journal: Mar Drugs Date: 2022-05-24 Impact factor: 6.085