Literature DB >> 34972995

Induction and Detection of Mitophagy.

Maria A Yapryntseva1, Boris Zhivotovsky1,2, Vladimir Gogvadze3,4.   

Abstract

Mitophagy, a process of selective elimination of mitochondria by autophagy, is a mechanism of mitochondrial quality control that maintains mitochondrial network functionality. The elimination of damaged mitochondria through autophagy requires two steps: induction of general autophagy and priming of damaged mitochondria for selective autophagic recognition. Mitophagy impairment is linked to various pathologies; thus, removal of malfunctioning or even harmful mitochondria is vital to cellular physiology. Here, we describe methods that can be applied to the investigation of mitophagy.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Autophagy; Confocal microscopy; Flow cytometry; Mitochondria; Mitophagy; Respiration

Mesh：

Year:  2022        PMID： 34972995     DOI： 10.1007/978-1-0716-2071-7_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

1.  Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging.

Authors:  John J Lemasters
Journal:  Rejuvenation Res       Date:  2005       Impact factor: 4.663

Review 2.  Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.

Authors:  Jesse S Kerr; Bryan A Adriaanse; Nigel H Greig; Mark P Mattson; M Zameel Cader; Vilhelm A Bohr; Evandro F Fang
Journal:  Trends Neurosci       Date:  2017-02-09       Impact factor: 13.837

Review 3.  Parkin and mitophagy in cancer.

Authors:  J P Bernardini; M Lazarou; G Dewson
Journal:  Oncogene       Date:  2016-09-05       Impact factor: 9.867

4.  Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa.

Authors:  Pablo Ibáñez; Suzanne Lesage; Ebba Lohmann; Stéphane Thobois; Giuseppe De Michele; Michel Borg; Yves Agid; Alexandra Dürr; Alexis Brice
Journal:  Brain       Date:  2006-01-09       Impact factor: 13.501

5.  Hydrogen peroxide-induced mitophagy contributes to laryngeal cancer cells survival via the upregulation of FUNDC1.

Authors:  L Hui; H Wu; T-W Wang; N Yang; X Guo; X-J Jang
Journal:  Clin Transl Oncol       Date:  2018-10-03       Impact factor: 3.405

Review 6.  Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases.

Authors:  Xinnan Li; Longjian Huang; Jiaqi Lan; Xinhong Feng; Pingping Li; Lei Wu; Ying Peng
Journal:  Pharmacol Res       Date:  2020-10-11       Impact factor: 7.658

Review 7.  Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

Authors:  Thanh N Nguyen; Benjamin S Padman; Michael Lazarou
Journal:  Trends Cell Biol       Date:  2016-06-10       Impact factor: 20.808

8.  High expression of FUNDC1 predicts poor prognostic outcomes and is a promising target to improve chemoradiotherapy effects in patients with cervical cancer.

Authors:  Hailing Hou; Puchun Er; Jingjing Cheng; Xiuli Chen; Xiaofeng Ding; Yuwen Wang; Xi Chen; Zhiyong Yuan; Qingsong Pang; Ping Wang; Dong Qian
Journal:  Cancer Med       Date:  2017-07-18       Impact factor: 4.452

9.  FUN14 domain-containing 1 promotes breast cancer proliferation and migration by activating calcium-NFATC1-BMI1 axis.

Authors:  Lianpin Wu; Donghong Zhang; Li Zhou; Yuqing Pei; Yixuan Zhuang; Wei Cui; Jiongyu Chen
Journal:  EBioMedicine       Date:  2019-02-23       Impact factor: 8.143

Review 10.  A Healthy Heart and a Healthy Brain: Looking at Mitophagy.

Authors:  Hongke Luo; Ruohan Zhang; Judith Krigman; Allison McAdams; Serra Ozgen; Nuo Sun
Journal:  Front Cell Dev Biol       Date:  2020-05-06
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.