Literature DB >> 34972974

Pulmonary Toxicities of Immunotherapy.

Mehmet Altan1, Linda Zhong2, Vickie R Shannon3, Ajay Sheshadri3.   

Abstract

Immune checkpoint inhibitors are a form of immunotherapy that are increasingly being used in a wide variety of cancers. Immune-related adverse events (irAEs) pose a major challenge in the treatment of cancer patients. Pneumonitis, the most common lung irAE, can cause significant disruptions in the treatment of cancer and may be life-threatening. The goal of this chapter is to instruct readers on the incidence and clinical manifestations of pneumonitis and to offer guidance in the evaluation and treatment of patients with pneumonitis.
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Entities:  

Keywords:  Checkpoint inhibitors; Diffuse alveolar damage; Hypersensitivity pneumonitis; Immune-related adverse event; Nonspecific interstitial pneumonia; Organizing pneumonia; Pneumonitis; Thoracic imaging

Mesh:

Substances:

Year:  2021        PMID: 34972974     DOI: 10.1007/978-3-030-79308-1_14

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  129 in total

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Journal:  Cell       Date:  2015-04-09       Impact factor: 41.582

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Review 4.  The PD-1 pathway in tolerance and autoimmunity.

Authors:  Loise M Francisco; Peter T Sage; Arlene H Sharpe
Journal:  Immunol Rev       Date:  2010-07       Impact factor: 12.988

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Journal:  Ann Oncol       Date:  2012-09       Impact factor: 32.976

Review 6.  PD-1 and its ligands in tolerance and immunity.

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Journal:  Annu Rev Immunol       Date:  2008       Impact factor: 28.527

Review 7.  Cancer immunotherapy.

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Journal:  Crit Rev Clin Lab Sci       Date:  2009       Impact factor: 6.250

8.  Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960.

Authors:  A S Ahmad; N Ormiston-Smith; P D Sasieni
Journal:  Br J Cancer       Date:  2015-02-03       Impact factor: 7.640

Review 9.  Cancer immunotherapy: the beginning of the end of cancer?

Authors:  Sofia Farkona; Eleftherios P Diamandis; Ivan M Blasutig
Journal:  BMC Med       Date:  2016-05-05       Impact factor: 8.775

10.  Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Authors:  Y Ishida; Y Agata; K Shibahara; T Honjo
Journal:  EMBO J       Date:  1992-11       Impact factor: 11.598

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