Literature DB >> 34972753

Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc.

Jongmin Kim1, Hyung-Joo Park2,3, Dae-Neung Lee1, Chul Ho Jang4.   

Abstract

BACKGROUND/AIM: Recently, hyaluronic acid disc has been known to enhance the success rate of fat myringoplasty. However, hyaluronic acid disc (Epidisc) is not covered by south Korean medical insurance. To date, fat myringoplasty using middle ear packing has rarely been reported. In this study, we studied whether middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of tympanic membrane perforation (TMP) closure without hyaluronic acid disc, regardless of perforation size. PATIENTS AND METHODS: Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at a tertiary referral center were enrolled, and the success rate and audiologic outcomes were analyzed.
RESULTS: The mean successful tympanic membrane (TM) closure rate was 88.0%. The success rate by different age groups showed no significant difference. Further, the size of perforation showed no significant difference, and the perforation site (anterior or posterior) was not significant. The preoperative mean thresholds of air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were 55.71, 12.98, and 42.73 dB respectively. The postoperative mean thresholds of AC, BC, and ABG were 23.67, 12.98, and 10.69 dB, respectively. Change in preoperative and postoperative hearing showed was statistically significant.
CONCLUSION: Middle ear packing by gelfoam combined with external ear canal packing using fibrin glue enabled stable adhesion between the remnant TM and the fat graft. Regardless of the size of the TMP, the success rate of the fat myringoplasty by our technique can be enhanced without use of hyaluronic acid disc.
Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Tympanic membrane; fat; myringoplasty; outcome.

Mesh:

Substances:

Year:  2022        PMID: 34972753      PMCID: PMC8765178          DOI: 10.21873/invivo.12729

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  30 in total

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2.  In response to Growth factors expression in hyaluronic acid fat graft myringoplasty.

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3.  The selection and strategy in otoendoscopic myringoplasty with autogenous adipose tissue.

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4.  Bilateral same day surgery for bilateral perforated chronic otitis media.

Authors:  M Sakagami; Y Mishiro; K Tsuzuki; T Seo; M Sone
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5.  The Long-Term Stability of Fat-Graft Myringoplasty in the Closure of Tympanic Membrane Perforations and Hearing Restoration.

Authors:  Jae Sang Han; Jung Ju Han; Jung Mee Park; Jae-Hyun Seo; Kyoung Ho Park
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  2020-12-18       Impact factor: 1.538

6.  Adipose myringoplasty in children.

Authors:  A E Deddens; H R Muntz; R P Lusk
Journal:  Laryngoscope       Date:  1993-02       Impact factor: 3.325

7.  Closure of tympanic membrane perforations by the use of fat.

Authors:  J C Ringenberg
Journal:  Laryngoscope       Date:  1978-06       Impact factor: 3.325

8.  Antifibrotic effect of dexamethasone/alginate-coated silicone sheet in the abraded middle ear mucosa.

Authors:  Chul Ho Jang; Seung Hyun Ahn; Geun Hyung Kim
Journal:  Int J Biol Macromol       Date:  2016-04-13       Impact factor: 6.953

9.  Effect of anti-adhesion barrier solution containing ciprofloxacin-hydrocortisone on abraded mucosa with otitis media.

Authors:  Chul Ho Jang; Yong Beom Cho; Cheol Hee Choi; Jun Sik Lee; Sung In Kang
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2012-10-06       Impact factor: 1.675

10.  Influence of size and site of perforation on fat graft myringoplasty.

Authors:  Taylan Gun; Tevfik Sozen; Osman Fatih Boztepe; Ozer Erdem Gur; Nuray Bayar Muluk; Cemal Cingi
Journal:  Auris Nasus Larynx       Date:  2014-09-08       Impact factor: 1.863

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