| Literature DB >> 34971076 |
Rozalyn L Rodwin1, Wilhelmenia L Ross2, Jaime Rotatori1, Katherine Allen3, Claudia Auerbach1, Lyn M Balsamo1, Nina S Kadan-Lottick2.
Abstract
Chemotherapy-induced peripheral neuropathy (CIPN), a debilitating side effect of pediatric cancer therapy, can be challenging to diagnose. We estimated the prevalence of newly identified and previously diagnosed CIPN in the regional HEROS Childhood Cancer Survivorship Clinic. From 2016 to 2018, 148 survivors (45.3% female, age 17.1 [SD 7.7] years, 81.8% in ongoing routine oncology follow-up) had their initial survivorship evaluation at an average of 7.4 (SD 6.6) years from diagnosis. Fifty-six survivors (37.8%) had CIPN, of these 46 (82.1%) were newly identified. Our findings demonstrate CIPN may be missed in routine oncology care, and new methods are needed to screen for CIPN.Entities:
Keywords: chemotherapy-induced peripheral neuropathy; childhood cancer survivorship; late effects; platinum; vincristine
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Year: 2021 PMID: 34971076 PMCID: PMC8805800 DOI: 10.1002/pbc.29550
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN: 1545-5009 Impact factor: 3.167