Literature DB >> 34969737

Reirradiation Using 198Au Grain Brachytherapy for Recurrent Oral Cancer Cases Previously Treated by Definitive Radiotherapy.

Masaru Konishi1, Yuki Takeuchi2, Katsumaro Kubo2, Nobuki Imano2, Ikuno Nishibuchi2, Yuji Murakami2, Kiichi Shimabukuro3, Pongsapak Wongratwanich3, Naoya Kakimoto3, Yasushi Nagata2.   

Abstract

BACKGROUND/AIM: We investigated treatment outcomes and complications during reirradiation of patients with oral cancers. PATIENTS AND METHODS: Six patients who received definitive radiotherapy for oral cancer as the initial treatment and brachytherapy for recurrence were included. Local control and overall survival rates, soft tissue and mandibular complications, and tooth extraction were investigated.
RESULTS: The five-year local control and overall survival rates were 83.3% and 100%, respectively. The occurrence rate of grade 2 soft tissue and mandible complications was 33.3%, and the primary sites were the buccal mucosa and the floor of mouth. The positions of the extracted tooth in the two cases were adjacent to the tumor, and one case developed grade 2 complication of the mandible.
CONCLUSION: During recurrence of the buccal mucosa and the floor of mouth cancers, reirradiation should be avoided considering mandibular complications. To avoid reirradiation-related complications, tooth extraction near the radiation field should be avoided.
Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

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Keywords:  Oral cancer; brachytherapy; complication; radiotherapy; reirradiation

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Year:  2022        PMID: 34969737     DOI: 10.21873/anticanres.15485

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  1 in total

1.  Investigating the displacement of radio-active sources during gold-198 grain brachytherapy for hospitalized oral cancer patients.

Authors:  Masaru Konishi; Yuki Takeuchi; Katsumaro Kubo; Nobuki Imano; Ikuno Nishibuchi; Yuji Murakami; Kiichi Shimabukuro; Pongsapak Wongratwanich; Naoya Kakimoto; Yasushi Nagata
Journal:  J Contemp Brachytherapy       Date:  2022-03-23
  1 in total

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