Literature DB >> 34969257

Evaluation of Adherence to Guideline-Based Bone Mineral Density Screening in Veterans with HIV.

Christie G Turin1, Naveed Khanjee1, Katharine Breaux1,2, Reina Armamento-Villareal1,3, Maria C Rodriguez-Barradas1,2, Eva H Clark1,4,5.   

Abstract

People with HIV (PWH) have a higher prevalence of bone mineral density (BMD) loss compared to people without HIV. The Infectious Diseases Society of America (IDSA) recommends BMD screening through dual energy X-ray absorptiometry (DXA) in PWH starting at age 50. We aimed to evaluate adherence to this recommendation in a population of Veterans with HIV (VWH). Retrospective cross-sectional analysis of VWH followed from 2014 to 2018 at the Michael E. DeBakey VA Medical Center Infectious Diseases Clinic, Houston, Texas. We collected data through registry extraction and chart review. We calculated the percentage of VWH with timely BMD loss screening by DXA within 5 years of turning 50. Secondary outcomes included prevalence of osteopenia, osteoporosis, and vitamin D deficiency. We included data from 1,243 VWH. Their average age was 52 years (range 18-86). Most were male (95%), and 59% were black. Of the 346 VWH who turned 50 years old during the study period, 78 (22.5%) underwent DXA within 5 years. Of these, 42 (53.8%) had normal BMD, 28 (35.9%) had osteopenia, and 8 (10.3%) had osteoporosis. Nine hundred ninety-three (79.9%) VWH had available 25-hydroxyvitamin D levels; of these, 453 (45%) had normal levels, 304 (30.6%) had vitamin D insufficiency, 184 (18.5%) had vitamin D deficiency, and 52 (5.2%) had severe vitamin D deficiency. Fewer than 25% of eligible VWH underwent timely BMD loss screening by DXA per IDSA guidelines. Almost half of screened VWH showed evidence of BMD loss. Although limited by lack of follow-up and fracture data, this study emphasizes the importance of improving BMD loss screening in this vulnerable population.

Entities:  

Keywords:  HIV; bone mineral density; osteoporosis; screening; vitamin D

Mesh:

Year:  2022        PMID: 34969257      PMCID: PMC9464047          DOI: 10.1089/AID.2021.0095

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN: 0889-2229            Impact factor:   1.723


  36 in total

1.  Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy.

Authors:  P Tebas; W G Powderly; S Claxton; D Marin; W Tantisiriwat; S L Teitelbaum; K E Yarasheski
Journal:  AIDS       Date:  2000-03-10       Impact factor: 4.177

Review 2.  Which HIV patients should be screened for osteoporosis: an international perspective.

Authors:  Elena Alvarez; Waldo H Belloso; Mark A Boyd; Ahmet Ç Inkaya; Evelyn Hsieh; Andrew Kambugu; Greg Kaminski; Esteban Martinez; Hans-Jürgen Stellbrink; Sharon Walmsley; Todd T Brown; Patrick W G Mallon
Journal:  Curr Opin HIV AIDS       Date:  2016-05       Impact factor: 4.283

Review 3.  Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review.

Authors:  Todd T Brown; Roula B Qaqish
Journal:  AIDS       Date:  2006-11-14       Impact factor: 4.177

4.  Increased risk of fragility fractures among HIV infected compared to uninfected male veterans.

Authors:  Julie A Womack; Joseph L Goulet; Cynthia Gibert; Cynthia Brandt; Chung Chou Chang; Barbara Gulanski; Liana Fraenkel; Kristin Mattocks; David Rimland; Maria C Rodriguez-Barradas; Janet Tate; Michael T Yin; Amy C Justice
Journal:  PLoS One       Date:  2011-02-16       Impact factor: 3.240

5.  HIV-1 triggers apoptosis in primary osteoblasts and HOBIT cells through TNFalpha activation.

Authors:  Davide Gibellini; Elisa De Crignis; Cristina Ponti; Laura Cimatti; Marco Borderi; Matilde Tschon; Roberto Giardino; Maria Carla Re
Journal:  J Med Virol       Date:  2008-09       Impact factor: 2.327

6.  High risk and probability of progression to osteoporosis at 10 years in HIV-infected individuals: the role of PIs.

Authors:  Eugènia Negredo; Klaus Langohr; Anna Bonjoch; Núria Pérez-Alvárez; Carla Estany; Jordi Puig; Joaquim Rosales; Patricia Echeverría; Bonaventura Clotet; Guadalupe Gómez
Journal:  J Antimicrob Chemother       Date:  2018-09-01       Impact factor: 5.790

7.  Evaluation of Adherence to Dual-Energy X-Ray Absorptiometry Scan Ordering for Persons Living with HIV at a Tertiary Medical Center.

Authors:  Rebecca N Kumar; Mary C Masters; Janna Williams; Lindsay R Morrison; Shannon Galvin; Karen M Krueger
Journal:  AIDS Patient Care STDS       Date:  2021-02       Impact factor: 5.078

8.  Clinician's Guide to Prevention and Treatment of Osteoporosis.

Authors:  F Cosman; S J de Beur; M S LeBoff; E M Lewiecki; B Tanner; S Randall; R Lindsay
Journal:  Osteoporos Int       Date:  2014-08-15       Impact factor: 4.507

9.  Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in female mice.

Authors:  Kelly E Mercer; Rebecca A Wynne; Oxana P Lazarenko; Charles K Lumpkin; William R Hogue; Larry J Suva; Jin-Ran Chen; Andrew Z Mason; Thomas M Badger; Martin J J Ronis
Journal:  J Pharmacol Exp Ther       Date:  2012-08-14       Impact factor: 4.030

10.  Bone mineral density scans in veterans.

Authors:  Elizabeth Bass; Etienne Pracht; Philip Foulis
Journal:  Clin Interv Aging       Date:  2007       Impact factor: 4.458

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.