Literature DB >> 349691

Viremia in experimental Creutzfeldt-Jakob disease.

E E Manuelidis, E J Gorgacs, L Manuelidis.   

Abstract

Inoculation of the buffy coat of blood from guinea pigs infected with Creutzfeldt-Jakob disease resulted in passage of this disease to recipient animals. This demonstrates that there is a viremia in experimental Creutzfeldt-Jakob disease. These findings suggest that the hematogenous route may be implicated in the human infection and that the disease may possibly be transmitted by blood transfusions.

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Year:  1978        PMID： 349691     DOI： 10.1126/science.349691

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  31 in total

1.  Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells.

Authors:  M J Shlomchik; K Radebold; N Duclos; L Manuelidis
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-24       Impact factor: 11.205

2.  Follicular dendritic cells and dissemination of Creutzfeldt-Jakob disease.

Authors:  L Manuelidis; I Zaitsev; P Koni; Z Y Lu; R A Flavell; W Fritch
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

3.  Virus-like interference in the latency and prevention of Creutzfeldt-Jakob disease.

Authors:  Laura Manuelidis; Zhi Yun Lu
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-11       Impact factor: 11.205

4.  Proteomic analysis of host brain components that bind to infectious particles in Creutzfeldt-Jakob disease.

Authors:  Terry Kipkorir; Christopher M Colangelo; Laura Manuelidis
Journal:  Proteomics       Date:  2015-06-09       Impact factor: 3.984

5.  Levels of infectivity in the blood throughout the incubation period of hamsters peripherally injected with scrapie.

Authors:  P Casaccia; A Ladogana; Y G Xi; M Pocchiari
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

6.  Astrocyte gene expression in Creutzfeldt-Jakob disease.

Authors:  L Manuelidis; D M Tesin; T Sklaviadis; E E Manuelidis
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

7.  Nucleic acid binding proteins in highly purified Creutzfeldt-Jakob disease preparations.

Authors:  T Sklaviadis; A Akowitz; E E Manuelidis; L Manuelidis
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-15       Impact factor: 11.205

8.  Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays.

Authors:  Jason M Wilham; Christina D Orrú; Richard A Bessen; Ryuichiro Atarashi; Kazunori Sano; Brent Race; Kimberly D Meade-White; Lara M Taubner; Andrew Timmes; Byron Caughey
Journal:  PLoS Pathog       Date:  2010-12-02       Impact factor: 6.823

9.  A transmissible Creutzfeldt-Jakob disease-like agent is prevalent in the human population.

Authors:  E E Manuelidis; L Manuelidis
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

Review 10.  The development of virus-free labile blood derivatives--a review.

Authors:  A M Prince; B Horowitz; M S Horowitz; E Zang
Journal:  Eur J Epidemiol       Date:  1987-06       Impact factor: 8.082
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