Literature DB >> 3496860

Emergency portacaval shunt for variceal hemorrhage. A prospective study.

J P Villeneuve, G Pomier-Layrargues, L Duguay, R Lapointe, S Tanguay, D Marleau, B Willems, P M Huet, C Infante-Rivard, P Lavoie.   

Abstract

Emergency portacaval shunt for variceal bleeding is associated with a high operative mortality, particularly if used as a last resort. Because of this, a strong case has been made against emergency shunt. This report describes an experience with emergency portacaval shunt for the treatment of variceal bleeding when used systematically after hemodynamic stabilization and control of the bleeding episode with balloon tamponade, if necessary, in patients with mild or moderate liver disease. The population studied comprised 62 consecutive patients who rebled from varices while participating in a controlled trial of propranolol for the prevention of rebleeding. Of the 62 patients, nine died of massive hemorrhage and 53 survived the hemorrhage. Of the 53 survivors, 11 had severe liver disease and were not considered for shunt surgery. Of the remaining 42 patients with mild or moderate liver disease, 36 had emergency central portacaval shunt. The interval between endoscopic diagnosis of variceal bleeding and surgery averaged 19 +/- 3 hours (mean +/- SE). The operative mortality rate, defined as in-hospital mortality, was 19%. One- and 2-year survival rates were 78% and 71%, respectively. The incidence of postoperative hepatic encephalopathy was 36%; all patients responded favorably to protein restriction and lactulose. Thus, under specific conditions, emergency portacaval shunt results in an acceptable long-term survival rate. In patients with mild or moderate liver disease, emergency portacaval shunt should be considered when other forms of treatment for the prevention of variceal rebleeding have failed.

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Year:  1987        PMID: 3496860      PMCID: PMC1492922          DOI: 10.1097/00000658-198707000-00007

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  18 in total

1.  Life-threatening hemorrhage of the digestive tract in cirrhotic patients. An assessment of the postoperative mortality after emergency portacaval shunt.

Authors:  D Prandi; B Rueff; J Roche-Sicot; C Sicot; J N Maillard; J P Benhamou; R Fauvert
Journal:  Am J Surg       Date:  1976-02       Impact factor: 2.565

2.  Analysis of operative mortality after portal decompressive procedures in cirrhotic patients.

Authors:  I J Sarfeh; J A Carter; H F Welch
Journal:  Am J Surg       Date:  1980-08       Impact factor: 2.565

3.  Treatment of hepatic coma by exchange blood transfusion.

Authors:  C Trey; D G Burns; S J Saunders
Journal:  N Engl J Med       Date:  1966-03-03       Impact factor: 91.245

4.  Propranolol for the prevention of recurrent variceal hemorrhage: a controlled trial.

Authors:  J P Villeneuve; G Pomier-Layrargues; C Infante-Rivard; B Willems; P M Huet; D Marleau; A Viallet
Journal:  Hepatology       Date:  1986 Nov-Dec       Impact factor: 17.425

5.  The course of patients after variceal hemorrhage.

Authors:  D Y Graham; J L Smith
Journal:  Gastroenterology       Date:  1981-04       Impact factor: 22.682

6.  Failure of repeated injection sclerotherapy to improve long-term survival after oesophageal variceal bleeding. A five-year prospective controlled clinical trial.

Authors:  J Terblanche; P C Bornman; D Kahn; M A Jonker; J A Campbell; J Wright; R Kirsch
Journal:  Lancet       Date:  1983-12-10       Impact factor: 79.321

7.  Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and variceal hemorrhage.

Authors:  J P Cello; J H Grendell; R A Crass; D D Trunkey; E E Cobb; D C Heilbron
Journal:  N Engl J Med       Date:  1984-12-20       Impact factor: 91.245

8.  Variceal hemorrhage: a critical evaluation of survival analysis.

Authors:  J L Smith; D Y Graham
Journal:  Gastroenterology       Date:  1982-05       Impact factor: 22.682

9.  Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices.

Authors:  M S Barsoum; F I Bolous; A A El-Rooby; M A Rizk-Allah; A S Ibrahim
Journal:  Br J Surg       Date:  1982-02       Impact factor: 6.939

10.  Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.

Authors:  R Peto; M C Pike; P Armitage; N E Breslow; D R Cox; S V Howard; N Mantel; K McPherson; J Peto; P G Smith
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640

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  9 in total

Review 1.  Could there be light at the end of the tunnel? Mesocaval shunting for refractory esophageal varices in patients with contraindications to transjugular intrahepatic portosystemic shunt.

Authors:  Jessica Davis; Albert K Chun; Marie L Borum
Journal:  World J Hepatol       Date:  2016-07-08

Review 2.  The use and misuse of transjugular intrahepatic portasystemic shunts.

Authors:  A J Sanyal
Journal:  Curr Gastroenterol Rep       Date:  2000-02

3.  [Therapy of bleeding esophageal varices in West Germany--results of a survey].

Authors:  K W Steegmüller; D Schmidt; T Junginger
Journal:  Langenbecks Arch Chir       Date:  1991

4.  Randomized controlled trial of emergency transjugular intrahepatic portosystemic shunt versus emergency portacaval shunt treatment of acute bleeding esophageal varices in cirrhosis.

Authors:  Marshall J Orloff; Florin Vaida; Kevin S Haynes; Robert J Hye; Jon I Isenberg; Horacio Jinich-Brook
Journal:  J Gastrointest Surg       Date:  2012-09-25       Impact factor: 3.452

Review 5.  Complications and limitations of injection sclerotherapy in portal hypertension.

Authors:  N D Heaton; E R Howard
Journal:  Gut       Date:  1993-01       Impact factor: 23.059

Review 6.  Surgical management of acute variceal hemorrhage.

Authors:  L F Rikkers; G Jin
Journal:  World J Surg       Date:  1994 Mar-Apr       Impact factor: 3.352

Review 7.  The surgeon's role in the management of portal hypertension.

Authors:  J Terblanche
Journal:  Ann Surg       Date:  1989-04       Impact factor: 12.969

8.  Clinical results of the transjugular intrahepatic portosystemic shunt (TIPS) for the treatment of variceal bleeding.

Authors:  S W Han; Y E Joo; H S Kim; S K Choi; J S Rew; J K Kim; S J Kim
Journal:  Korean J Intern Med       Date:  2000-12       Impact factor: 2.884

9.  The transjugular intrahepatic portosystemic shunt in the treatment of portal hypertension: current status.

Authors:  Gilles Pomier-Layrargues; Louis Bouchard; Michel Lafortune; Julien Bissonnette; Dave Guérette; Pierre Perreault
Journal:  Int J Hepatol       Date:  2012-07-19
  9 in total

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