Literature DB >> 34966969

Adaptation to Antimicrobials and Pathogenicity in Mycoplasmas: Development of Ciprofloxacin-Resistance and Evolution of Virulence in Acholeplasma laidlawii.

E S Medvedeva1, A A Mouzykantov2, V V Kostenko1,3, N B Baranova1, M I Markelova1,3, R G Sabouni1,3, D R Khusnutdinova1,3, O A Chernova1, V M Chernov1.   

Abstract

For the first time it was shown that the development of resistance to ciprofloxacin in vitro in Acholeplasma laidlawii, a mycoplasma which is widely spread in nature and which is the main contaminant of cell cultures and vaccines, is associated with diverse pathways of virulence evolution: virulome and virulence differ significantly between ciprofloxacin-resistant strains, including those with the same level of antimicrobial resistance.
© 2021. Pleiades Publishing, Ltd.

Entities:  

Keywords:  Acholeplasma laidlawii; Drosophila melanogaster; ciprofloxacin-resistant strains; genomic profile; phenotypic resistance; vesicular proteome; virulence; virulome

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Year:  2021        PMID： 34966969     DOI： 10.1134/S1607672921060028

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  1 in total

1.  Multiple host transfers, but only one successful lineage in a continent-spanning emergent pathogen.

Authors:  Wesley M Hochachka; André A Dhondt; Andrew Dobson; Dana M Hawley; David H Ley; Irby J Lovette
Journal:  Proc Biol Sci       Date:  2013-09-07       Impact factor: 5.349
  1 in total
  1 in total

1.  Development of Resistance to Clarithromycin and Amoxicillin-Clavulanic Acid in Lactiplantibacillus plantarum In Vitro Is Followed by Genomic Rearrangements and Evolution of Virulence.

Authors:  V V Kostenko; A A Mouzykantov; N B Baranova; E A Boulygina; M I Markelova; D R Khusnutdinova; M V Trushin; O A Chernova; V M Chernov
Journal:  Microbiol Spectr       Date:  2022-05-17
  1 in total

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